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端粒（Telomere）是真核细胞染色体末端的多重复序列（TTAGGG）及其结合蛋白组成的特殊结构（图1），主要功能是保护染色体末端免于降解、融合和退化，从而保证细胞DNA及相关遗传信息的稳定和完整。端粒长度（Telomere length, TL）随着细胞分裂次数的增加而不断缩短，当TL不能再缩短时，细胞也就无法继续分裂，进而走向衰老、死亡或癌变。因此，TL是指征衰老和疾病（糖尿病、肺纤维化、心...
植物基因组学与新绿色革命论坛：Atypical disease resistance genes across the genome of wheat（2023.10.23日10:00）
植物基因组学 新绿色革命 麦类作物
2023/10/28
植物基因组学与新绿色革命论坛：Atypical disease resistance genes across the genome of wheat（2023.10.23日10:00）。
【致远名家讲堂】第三讲丨美国杜克大学何胜洋院士：Disease-Microbiome-Climate interactions in plants（图）
致远名家讲堂 第三讲 何胜洋 美国杜克大学 病害三角 植物病原物
2023/12/11
2023年9月13日，中国农业大学植物保护学院于植保楼报告厅开展第三期致远名家讲堂活动，特邀请美国科学院院士、美国杜克大学何胜洋教授主讲。本次活动线上线下同步进行，逾300名师生现场听讲，500余人参与线上直播活动。本次活动由彭友良教授和孙文献教授主持。
南京农业大学农学院《Plant Physiology》发表华健教授课题组“CHROMATIN REMODELING 11-dependent nucleosome occupancy affects disease resistance in rice”（图）
华健 基因转录 蛋白修饰
2023/10/28
染色质重塑主要包括围绕核小体的组蛋白修饰和染色质重塑蛋白介导的染色质构型调控。染色质重塑介导的基因转录表达调控是植物基因转录调控最重要的调控机制之一。然而，目前对于病原菌侵染诱导的寄主植物核小体动态变化及其与基因转录表达的关系尚不清楚。
New method tracking changes in blood vessels could advance brain disease detection（图）
血管变化 脑部疾病 成像技术 神经退行性疾病
2023/6/26
A new imaging technique opens a path toward long-term study of blood vessels in aging brains and could help predict neurodegenerative diseases decades before symptoms begin.
南京农业大学农学院《Remote Sensing of Environment》发表智慧农业团队“A disease-specific spectral index tracks Magnaporthe oryzae infectionin paddy rice from ground to space”（图）
智慧农业 时空动态 遥感监测 稻瘟病
2023/10/28
2023年2月25日，农学院智慧农业团队在国际顶级遥感期刊《Remote Sensing of Environment》发表了题为“A disease-specific spectral index tracks Magnaporthe oryzae infectionin paddy rice from ground to space”的研究论文，报道了他们在多尺度稻叶瘟敏感光谱指数构建，以及小...
《The overview of studies on huperzine A: a natural drug for the treatment of Alzheimer's disease》
中国科学院 上海药物研究所 阿尔茨海默病
2023/2/22
《The overview of studies on huperzine A: a natural drug for the treatment of Alzheimer's disease》
南京农业大学农学院《Molecular Plant》上发表王秀娥教授团队“A chromosome-scale genome assembly of Dasypyrum villosum provides insights into its application as a broad-spectrum disease resistance resource for wheat improvement”（图）
王秀娥 小麦遗传育种 基因 栽培
2023/10/28
2023年2月6日，南京农业大学农学院细胞遗传研究所作物遗传与种质创新国家重点实验室小麦遗传育种创新团队在《Molecular Plant》杂志上发表了题为“A chromosome-scale genome assembly of Dasypyrum villosum provides insights into its application as a broad-spectrum disea...
The following press release was issued today by the Broad Institute of MIT and Harvard.
Every day, billions of red blood cells pass through the spleen, an organ that is responsible for filtering out old or damaged blood cells. This task is made more difficult when the blood cells are mis...
New technologies reveal cross-cutting breakdowns in Alzheimer’s disease（图）
阿尔茨海默病 交叉细分 单细胞分析 脑细胞
2023/6/21
After decades of fundamental scientific and drug discovery research, Alzheimer’s disease has remained inscrutable and incurable, with a bare minimum of therapeutic progress. But in a new review articl...
Neurodegenerative disease can progress in newly identified patterns（图）
神经退行性疾病 模式进展 机器学习 ALS 健康下降
2023/6/21
Neurodegenerative diseases — like amyotrophic lateral sclerosis (ALS, or Lou Gehrig's disease), Alzheimer’s, and Parkinson’s — are complicated, chronic ailments that can present with a variety of symp...
Landscape and climate factors can predict prevalence of Lyme disease bacteria（图）
气候因素 莱姆病细菌 公共卫生
2023/7/7
Predicting Lyme disease hotspots can help public health officials guide resources and proactive messaging to the public. But the ecology of the disease is complex, involving various host animals, blac...
Fibrosis is the thickening of various tissues caused by the deposition of fibrillar extracellular matrix (ECM) in tissues and organs as part of the body’s wound healing response to various forms of da...
A combination of ecological field methods and cutting-edge artificial intelligence has helped an interdisciplinary research group detect eelgrass wasting disease at nearly three dozen sites along a 1,...