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Understanding the allosteric mechanism of the Escherichia coli Hsp70 molecular chaperone, DnaK
Hsp70 Protein aggregation Enzyme Polypeptide Protein function Nucleotides. The ATP hydrolysis
2014/12/11
The Hsp70 family molecular chaperones prevent protein aggregation under heat shock conditions. They are highly conserved, and have a N-terminal ATPase domain, which binds and hydrolyzes ATP, and a C-t...
An Integrative Approach Towards Understanding The Structure- Function Relationship Of The Epigenetic Regulator Methyl Cpg Binding Protein 2
Pure sciences Biological sciences Epigenetic regulator Methyl CpG Binding protein 2 Binding dynamics of caps Chromatin architectural proteins (caps) Intrinsically disordered protein Nucleosome Protein folding
2014/12/10
Methyl CpG binding protein 2 (MeCP2) is a methylated DNA binding protein which, when mutated, leads to a severe neurodevelopmental disorder known as Rett syndrome (RTT). In the present work I have sho...