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Stories and Challenges of Genome Wide Association Studies in Livestock — A Review
QTL Livestock Genome-wide Association
2016/5/18
Undoubtedly livestock is one of the major contributors to the economy of any country. The economic value of livestock includes meat, dairy products, fiber, fertilizer etc. Understanding and identifyin...
Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium
arachidonic acid genome-wide association meta-analysis phospholipid trans fatty acids
2018/12/20
Background: Circulating trans fatty acids (TFAs), which cannot be synthesized by humans, are linked to adverse health outcomes. Although TFAs are obtained from diet, little is known about subsequent i...
A Bayesian Method for Detecting and Characterizing Allelic Heterogeneity and Boosting Signals in Genome-Wide Association Studies
Bayesian Method Detecting Characterizing Allelic Heterogeneity Boosting Signals Genome-Wide Association Studies
2010/11/16
The standard paradigm for the analysis of genome-wide association studies involves carrying out association tests at both typed and imputed SNPs. These methods will not be optimal for detecting the si...
Methodological Issues in Multistage Genome-Wide Association Studies
Methodological Issues Multistage Genome-Wide Association Studies
2010/11/16
Because of the high cost of commercial genotyping chip technologies, many investigations have used a two-stage design for genome-wide association studies, using part of the sample for an initial disco...