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Signal Transduction and Targeted Therapy丨柳素玲团队等发现趋化因子CCL20通过重塑肿瘤免疫微环境促进乳腺癌进展的新机制（图）
乳腺癌 肿瘤干细胞 肿瘤恶性 生物医学研究院
2023/4/13
肿瘤微环境（tumor microenvironment，TME）在肿瘤恶性和治疗抵抗中发挥着重要作用。近年来，根据TME特点挖掘潜在靶点并开发安全有效的免疫疗法逐渐成为乳腺癌治疗的研究热点。2018年7月27日，复旦大学生物医学研究院/附属肿瘤医院柳素玲团队在PLOS Biology杂志在线发表了题为CCL20 triggered by chemotherapy hinders the ther...
牛侨教授团队在《Molecular Therapy-Nucleic Acid》发文：利用全转录组测序揭示预防和治疗铝神经毒性作用的生物靶点（图）
牛侨教授 山西医科大学 公共卫生学
2023/12/25
2021年11月，山西医科大学公共卫生学院劳动卫生学教研室牛侨教授团队在《Molecular Therapy-Nucleic Acid》（JCR1区、中科院2区，影响因子8.886）在线发表题为“Whole-transcriptome analysis of aluminum-exposed rat hippocampus and identifification of ceRNA network...
周玉峰团队在《Signal Transduction and Targeted Therapy》上发表Covid-19感染的细胞因子风暴信号通路和治疗的长篇综述（图）
COVID-19 周玉峰团队 细胞因子 免疫球蛋白 糖皮质激素
2023/4/17
2021年7月7日，复旦大学生物医学研究院/附属儿科医院周玉峰研究员与英国格拉斯哥大学/深圳大学医学院徐大模教授合作在Signal Transduction and Targeted Therapy杂志上发表了一篇题为The signal pathways and treatment of cytokine storm in COVID-19 的长篇综述。
近日，山西医科大学基础医学院细胞生理学教育部重点实验室祁金顺教授团队与贺培凤教授带领的健康大数据团队进行的校内合作成果，在国际阿尔茨海默病协会（ADI）会刊《Alzheimer's Research & Therapy》（中科院期刊分区2区，影响因子：6.116）发表了题为《Trichostatin A ameliorates Alzheimer's disease-related patholo...
Effectiveness of convalescent plasma therapy in severe COVID-19 patients
COVID-19 convalescent plasma treatment outcome pilot project
2020/6/12
Currently, there are no approved specific antiviral agents for novel coronavirus disease 2019 (COVID-19). In this study, 10 severe patients confirmed by real-time viral RNA test were enrolled prospect...
A systematic review and meta-analysis of nutrition therapy compared with dietary advice in patients with type 2 diabetes
dietary advice individualized nutrition therapy meta-analysis review type 2 diabetes
2018/11/21
Background: Despite recommendations, many patients with type 2 diabetes receive dietary advice from nurses or doctors instead of individualized nutrition therapy (INT) that is provided by a dietitian.
Higher dietary cholesterol and ω-3 fatty acid intakes are associated with a lower success rate of Helicobacter pylori eradication therapy in Japan
Helicobacter pylori dietary factors cholesterol omega 3 fatty acids eradication therapy
2018/11/15
Background:Helicobacter pylori infection is a known risk factor for duodenal ulcers, gastritis, and gastric cancer. The eradication of H. pylori is successful in treating these disorders; however, the...
Continuous renal replacement therapy: a potential source of calories in the critically ill
nutrition CRRT CVVH citrate anticoagulation caloric uptake
2018/11/14
Background: Overfeeding can lead to multiple metabolic and clinical complications and has been associated with increased mortality in the critically ill. Continuous venovenous hemofiltration (CVVH) re...
Folic acid therapy reduces serum uric acid in hypertensive patients: a substudy of the China Stroke Primary Prevention Trial (CSPPT)
controlled hyperuricemia olic acid supplementation new-onset hyperuricemia total homocysteine uric acid concentrations
2018/11/13
Background: The effect of folic acid supplementation on uric acid (UA) concentrations is still inconclusive.
Men’s health supplement use and outcomes in men receiving definitive intensity-modulated radiation therapy for localized prostate cancer
complementary and alternative medicine dietary supplements men’s health prostate cancer radiation therapy vitamins multivitamins
2018/12/19
Background: Approximately 50% of newly diagnosed cancer patients start taking dietary supplements. Men’s health supplements (MHSs), which we define as supplements that are specifically marketed with t...
Predictors of failure of fish-oil therapy for intestinal failure–associated liver disease in children
cholestasis fish oil fish oil lipid emulsion intestinal failure intestinal failure–associated liver disease Omegaven parenteral fish oil
2018/12/14
Background: Parenteral fish-oil (FO) therapy is a safe and effective treatment for intestinal failure–associated liver disease (IFALD). Patients whose cholestasis does not resolve with FO may progress...
Effect of highly active antiretroviral therapy on fat, lean, and bone mass in HIV-seropositive men and women
lipodystrophy fat redistribution lean body mass
2016/6/14
Alterations in body composition have been
reported in HIV-positive adults receiving highly active antiretroviral
therapy (HAART), but the magnitude and potential determinants
of these changes are u...
Fat malabsorption in cystic fibrosis patients receiving enzyme replacement therapy is due to impaired intestinal uptake of long-chain fatty acids
fat malabsorption fat balance lipolysis
2016/5/27
Pancreatic enzyme replacement therapy frequently
fails to correct intestinal fat malabsorption completely in
cystic fibrosis (CF) patients. The reason for this failure is
unknown.
The changing landscape of systemic therapy in advanced pancreatic cancer
Pancreatic cancer disease congenital resistant to treatment
2017/2/22
Pancreatic cancer is a highly lethal disease due to its late presentation and its innate resistance to treatment. Although much research has been conducted in order to discover and develop new therape...
Comparison of iron status 28 d after provision of antimalarial treatment with iron therapy compared with antimalarial treatment alone in Ugandan children with severe malaria
hepcidin iron malaria timing of iron supplementation inflammation
2018/11/28
Background: The provision of iron with antimalarial treatment is the standard of care for concurrent iron deficiency and malaria. However, iron that is given during a malaria episode may not be well a...