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Genetic influences on schizophrenia and subcortical brain volumes:large-scale proof of concept
schizophrenia subcortical brain volumes large-scale proof of concept
2016/5/3
Schizophrenia is a devastating psychiatric illness with high heritability. Brain structure and function differ, on average, between people with schizophrenia and healthy individuals. As common genetic...
Dimensional approaches to experimental psychopathology of schizophrenia: shift learning and report of psychotic-like experiences in college students
Attentional set shifting Concept learning Negative Schizotypy Reversal shift learning Rule learning Social/interpersonal deficits Stimulus discrimination
2015/7/30
Adopting a dimensional approach to experimental psychopathology, and taking into account inconsistencies in the previous literature, we examined whether reports of psychotic-like experiences in underg...
Psychosocial and Biological Factors Contributing to Body Weight Gain in Schizophrenia
Body weight gain Psychosocial factors Biological factors Schizophrenia Overweight Obesity
2015/7/21
Overweight and obesity are frequently reported to be a significant issue in schizophrenia resulting in the inherent complications of these disorders. Body weight gain also commonly results from treatm...
Patterns of Gray Matter Abnormalities in Schizophrenia Based on an International Mega-analysis
independent component analysis schizophrenia source-based morphometry symptoms voxel-based morphometry
2015/5/5
Analyses of gray matter concentration (GMC) deficits in patients with schizophrenia (Sz) have identified robust changes throughout the cortex. We assessed the relationships between diagnosis, overall ...
A direct molecular link between the autism candidate gene RORa and the schizophrenia candidate MIR137
direct molecular link autism candidate gene RORa the schizophrenia candidate MIR137
2015/5/5
Retinoic acid-related orphan receptor alpha gene (RORa) and the microRNA MIR137 have both recently been identified as novel candidate genes for neuropsychiatric disorders. RORa encodes a ligand-depend...
No effect of schizophrenia risk genes MIR137, TCF4, and ZNF804A on macroscopic brain structure
miR-137 TCF4 ZNF804A Genetic neuroimaging Brain volume
2015/5/5
Single nucleotide polymorphisms (SNPs) within the MIR137, TCF4, and ZNF804A genes show genome-wide association to schizophrenia. However, the biological basis for the associations is unknown. Here, we...
Hypomethylation of the Paternally Inherited LRRTM1 Promoter Linked to Schizophrenia
epigenetics parental imprint sibling pair psychosis
2015/5/5
Epigenetic effects on psychiatric traits remain relatively understudied, and it remains unclear what the sizes of individual epigenetic effects may be, or how they vary between different clinical popu...
Population-based linkage analysis of schizophrenia and bipolar case–control cohorts identifies a potential susceptibility locus on 19q13
schizophrenia segmental sharing case–control genome scan
2015/4/8
Population-based linkage analysis is a new method for analysing genomewide single nucleotide polymorphism (SNP) genotype data in case–control samples, which does not assume a common disease, common va...
Veterans and non-veterans with schizophrenia : a grounded theory comparison of perceptions of self, illness, and treatment
schizophrenia stigma self Veteran
2015/1/9
This study investigates differences between Veterans and non-Veterans with severe mental illness (SMI) regarding perceptions of their illness, themselves, and treatment. I compare patient interviews (...
TIME SKIPS AND TRALFAMADORIANS: CULTURAL SCHIZOPHRENIA AND SCIENCE FICTION IN KURT VONNEGUT’S SLAUGHTERHOUSE-FIVE AND THE SIRENS OF TITAN
Kurt Vonnegut Slaughterhouse-five The Sirens of Titan Science Fiction Cultural Schizophrenia
2015/1/8
In his novels Slaughterhouse-five and The Sirens of Titan, Kurt Vonnegut explores issues of cultural identity in technologically-advanced societies post-World War II. With the rise of globalization an...
Coping with Positive and Negative Symptoms of Schizophrenia
schizophrenia negative symptoms coping strategies
2014/11/10
Objective: Although coping with positive symptoms of schizophrenia has been studied widely, few studies have examined coping with negative symptoms. This study compares the appraisal of stressfulness ...
Association Between Upstream Purine Complexes of Human Caveolin-1 Gene and Schizophrenia in Qazvin Province of Iran
Caveolin-1 Schizophrenia Iran
2015/10/16
Background: Caveolin is a multifunctional and scaffolding membrane protein, which involves cholesterol trafficking to plasma lipid microdomain. It organizes and targets synaptic parts of the neurotran...
The Distribution of the Stress Protein HSP70 in the Cerebellum of Patients with Schizophrenia
Biological Marker Post Mortem Heat Shock Protein Cerebellum Schizophrenia
2013/1/30
Data accumulated from neuro-imaging, clinical and morphological studies suggest that the cerebellum is involved in cognitive functions and thus may be important in the etiopathogenesis of schizophreni...
Analysis of cross-correlations in electroencephalogram signals as an approach to proactive diagnosis of schizophrenia
Flicker-noise spectroscopy Frequency-phase synchronization Cross-correlations Electroencephalogram signals
2011/8/3
Abstract: We apply flicker-noise spectroscopy (FNS), a time series analysis method operating on structure functions and power spectrum estimates, to study the clinical electroencephalogram (EEG) signa...
Dermatoglyphics as markers of prenatal disturbances in schizophrenia: a case-control study
Schizophrenia dermatoglyphic gender comparison finger ridge count a-b ridge count c-d ridge count
2010/12/21
Several studies have reported the importance of dermatoglyphics as markers of a prenatal disturbance in patients with schizophrenia. Due to the fact that finger- and handprints are formed by the end o...