搜索结果: 1-15 共查到“知识库 the cancer cells”相关记录19条 . 查询时间(0.093 秒)
EFFECTS OF CHOLINE KINASE ACTIVITY ON PHOSPHOLIPID METABOLISM AND MALIGNANT PHENOTYPE OF PROSTATE CANCER CELLS
hypoxia cancer HIF
2015/5/25
High choline uptake and increased choline kinase activity have been reported in many cancers. This has motivated the use of choline as a biomarker for tumor imaging. Tumors in general are heterogeneou...
An inhibitor of the mitotic kinase, MPS1, is selective towards pancreatic cancer cells
CIN70 MPS1 kinase inhibitor pancreatic cancer
2015/5/21
The abysmal five year pancreatic cancer survival rate of less than 6% highlights the need for new treatments for this deadly malignancy. Cytotoxic drugs normally target rapidly dividing cancer cells b...
Effects of Histone Deacetylase Inhibitors on Vitamin D Activity in Human Breast Cancer Cells
Sulforaphane histone deacetylase inhibitors vitamin D receptor
2014/11/7
Breast cancer is one of the leading causes of death in women cancer cases worldwide. Cancer is the result of environmental and genetic factors that contribute to alterations in cellular control, proli...
Decreased Autocrine EGFR Signaling in Metastatic Breast Cancer Cells Inhibits Tumor Growth in Bone and Mammary Fat Pad
autocrine signaling bone marrow cells breast cancer
2014/11/6
Breast cancer metastasis to bone triggers a vicious cycle of tumor growth linked to osteolysis. Breast cancer cells and osteoblasts express the epidermal growth factor receptor (EGFR) and produce ErbB...
Consequences of telomerase inhibition and telomere dysfunction in BRCA1 mutant cancer cells
telomerase BRCA breast cancer telomeres
2015/5/21
Telomere maintenance is a critical component of genomic stability. An increasing body of evidence suggests BRCA1, a tumor suppressor gene with a variety of functions including DNA repair and cell cycl...
Induction of apoptosis in human bladder cancer cells by green tea catechins
apoptosis human bladder cancer cells
2009/12/16
Cell culture and animal studies have demonstrated strong chemopreventative effects of green tea and its associated polyphenols in multiple cancers, though the exact mechanisms of action are not well u...
Ag nanoparticles sensitize IR-induced killing of cancer cells
Ag nanoparticles sensitize IR-induced cancer cells
2010/7/16
Ag nanoparticles sensitize IR-induced killing of cancer cells.
Characterization of Berberine on Human Cancer Cells in Culture
Cytotoxicity DNA damage repair cellular localization berberine
2009/6/25
Berberine originates from a Chinese herbal medicine and possesses a wide variety of anti-cancer activities. In this study, the killing effect of berberine on nasopharyngeal carcinoma cells (NPC/HK1) ...
Induction of Apoptosis in Cultured Human Stomach Cancer Cells by Potato Anthocyanins and Its Inhibitory Effects on Growth of Stomach Cancer in Mice
anthocyanin-containing potatoes stomach cancer KATO III cells DNA fragmentation
2009/6/18
Anthocyanins prepared from colored potatoes induce apoptosis in cultured human stomach cancer KATO III cells. Morphological change indicating apoptotic bodies and DNA fragmentations were observed in c...
The effect of hyperbaric oxygen on human oral cancer cells
Apoptosis mice Body Weight Carcinoma Cell Line Tumor
2009/6/4
Discoveries of the beneficial cellular and biochemical effects have strengthened the rationale for the administration of hyperbaric oxygen therapy (HBO2) as an adjunctive therapy for the treatment of ...
Bax/Bcl-2 expression levels of 2-methoxyestradiol-exposed esophageal cancer cells
Bax/Bcl-2 expression 2-methoxyestradiol-exposed esophageal cancer cells
2009/3/2
2-Methoxyestradiol (2ME), an endogenous metabolite of 17β-estradiol, has been reported to play an active role in the induction of apoptosis in both proliferating endothelial and cancer cells. Since ...
Inhibition effect of Oncostatin M on metastatic human lung cancer cells 95-D in vitro and on murine melanoma cells B16BL6 in vivo
Oncostatin M metastatic human lung cancer cells 95-D murine melanoma cells B16BL6
2009/3/2
Oncostatin M (OSM) is a multifunctional regulator of cell growth and differentiation. It inhibits the growth of many types of tumor cells, but its role in metastasis is unknown. We studied the human...
Period is involved in the proliferation of human pancreatic MIA-PaCa2 cancer cells by TNF-α
proliferation human pancreatic MIA-PaCa2 cancer cells TNF-α
2009/3/2
Recent studies have found alterations to clock genes in several forms of cancer. Period (Per) gene plays an important role in the circadian system, the cell cycle, the induction of apoptosis, and DN...
Androgen regulation of the human ornithine decarboxylase promoter in prostate cancer cells
Androgen receptor gene regulation
2009/2/17
We studied the response of the human ornithine decarboxylase (ODC) promoter to androgen in human prostate cancer cell lines. In the well-differentiated, androgen-sensitive human prostate cancer li...
Biphasic Effect of Androgens on Prostate Cancer Cells and Its Correlation With Androgen Receptor Coactivator Dopa Decarboxylase
Neuroendocrine differentiation methyltoenolone cDNA microarray
2008/12/24
The aim of this study was to explore the mechanism underlying the dual effect of androgen on prostate cancer cells and further explore its correlation with dopa decarboxylase (DDC), an androgen r...