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Systems Pharmacology Dissection of Multi-Scale Mechanisms of Action of Huo-Xiang-Zheng-Qi Formula for the Treatment of Gastrointestinal Diseases
TCM gastrointestinal diseases functional dyspepsia systems pharmacology Huo-xiang-zheng-qi compatibility theory
2023/6/21
Multi-components Traditional Chinese Medicine (TCM) treats various complex diseases (multi-etiologies and multi-symptoms) via herbs interactions to exert curative efficacy with less adverse effects. H...
Systems Pharmacology Dissection of Multiscale Mechanisms of Action for Herbal Medicines in Treating Rheumatoid Arthritis
Rheumatoid arthritis TCM Systems-Pharmacology MD MM-PBSA
2023/6/19
As a chronic inflammatory and angiogenic disease with increased morbidity and mortality, rheumatoid arthritis (RA) is characterized by the proliferation of synovial tissue and the accumulation of exce...
糖尿病和高血压是临床上最为常见的两种疾病，它们之间通过多种病理生理机制相互联系。高血压是导致2型糖尿病（Type 2 Diabetes Mellitus, T2DM）高风险因素。临床研究表明，高血压患者患T2DM的可能性几乎是正常血压患者的2.5倍，同时约70%-80%的T2DM患者有高血压。这两种疾病并存，病理生理变化相互促进形成恶性循坏，导致较高的死亡率和发病率，严重威胁人类健康。因此研发同时...
2021年7月，山西医科大学基础医学院药理教研室章毅教授团队2021年年内再次在《Frontiers in Pharmacology》（中科院2区，影响因子5.8）上发表了题为“Sphingosine 1-phosphate stimulates insulin secretion and improves cell survival by blocking voltage-dependent K...
糖尿病是一类以高血糖为主要特征的慢性代谢性疾病，目前已在全球广泛蔓延。根据国际糖尿病联盟（International Diabetes Federation, IDF）颁布的第九版世界糖尿病地图显示，2019年全球约有4.63亿成人(20-79岁)患糖尿病，预计到2030年糖尿病患病人数将达到5.78亿。若按照此趋势持续下去，2045年全球将有7亿糖尿病患者。因此，糖尿病已成为21世纪全球范围内面...
Integrating a New Medicinal Chemistry and Pharmacology Course Sequence into the PharmD Curriculum
medicinal chemistry pharmacology integration alignment curriculum
2018/7/24
Objective. To evaluate the implementation of an integrated medicinal chemistry/pharmacology course sequence and its alignment with a therapeutics series.
Design. Each topic was divided into modules c...
Knowledge of Pharmacology of Analgesics Among Nurses in a Tertiary Centre
Knowledge of Pharmacology Nurses Analgesics Questionnaire study Tertiary centre
2015/7/10
Objectives: To evaluate the knowledge of nurses about the analgesics they administer in our hospital. Methodology: A total of 102 nurses completed the questionnaire which included 20 multiple choice q...
Test-Enhanced Learning in an Immunology and Infectious Disease Medicinal Chemistry/Pharmacology Course
test-enhanced learning retrieval practice curriculum assessment
2018/9/4
Objective. To develop a series of active-learning modules that would improve pharmacy students’ performance on summative assessments.
Design. A series of optional online active-learning modules conta...
Integrating a New Medicinal Chemistry and Pharmacology Course Sequence into the PharmD Curriculum
medicinal chemistry pharmacology integration alignment curriculum
2016/3/2
Objective.To evaluate the implementation of an integrated medicinal chemistry/pharmacology course
sequence and its alignment with a therapeutics series.
Design. Each topic was divided into modules c...
STRUCTURAL BIOLOGY AND PHARMACOLOGY OF HUMAN CATHEPSIN A AND NEURAMINIDASE 1
Cathepsin A Neuraminidase Lysosomal storage diseases sialidosis Galactosialidosis serine carboxypeptidase
2014/12/10
Human cathepsin A (also known as Protective Protein/Cathepsin A, PPCA; E.C. 3.4.16.5) is a lysosomal serine carboxypeptidase. Cathepsin A is also involved in a complex with two other lysosomal enzymes...
Evaluating the Relationship Between General Health Vocabulary and Student Achievement in Pharmacology
achievement general health vocabulary multilingual pharmacology pharmacy
2018/7/10
Objective. To determine whether achievement in pharmacology is related to students’ general health vocabulary knowledge.
Methods. Students registered for the pharmacology modules in the second (n=117...
Student Engagement in Pharmacology Courses Using Online Learning Tools
engagement e-tools pharmacology online instruction Internet
2018/6/25
Objective. To assess factors influencing student engagement with e-tools used as a learning supplement to the standard curriculum in pharmacology courses.
Design. A suite of 148 e-tools (interactive ...
Teaching the Pharmacology of Antiarrhythmic Drugs
arrhythmia antiarrhythmic agents pharmacology integrated curriculum
2018/5/31
Objective. To provide doctor of pharmacy (PharmD) students with highly integrated, comprehensive and up-to-date instruction related to the pharmacology of antiarrhythmic drugs.
Design. Students were ...
REVIEW OF STUDIES ON CHEMICAL CONSTITUENTS AND PHARMACOLOGY OF GENUS ACORUS IN CHINA
Acorus A. tatarinowii Acori chemical constituents pharmacological studies
2009/6/1
Chemical research showed that drug Acori contain volatile oil, and that the quality of volatile oil (0.53% ~ 2.l5 % )is different based on the drug's origin. The volatile oil mainly contain β-asarone,...
The Pharmacology of Immunosuppression
immunosuppression pharmacology organ transplantation autoimmune disease immune system
2018/5/17
Objective. To provide students with a comprehensive, integrated presentation on the pharmacology of immuosuppression.
Design. Course content on the pharmacology of immunosuppression relating to organ...