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Hand2 function within non-cardiomyocytes regulates cardiac morphogenesis and performance
Notch Signaling EphrinB2 bHLH Transcription Factor
2015/5/21
The heart is a complex organ that is composed of numerous cell types, which must integrate their programs for proper specification, differentiation, and cardiac morphogenesis. During cardiac developme...
In Situ Real-Time Chemiluminescence Imaging of Reactive Oxygen Species Formation from Cardiomyocytes
Chemiluminescence Cardiomyocytes
2009/9/4
We have applied the highly sensitive chemiluminescence (CL) imaging technique to investigate the in situ ROS formation in cultured monolayers of rat H9c2 cardiomyocytes. Photon emission was detected v...
Changes of HCN gene expression and If currents in Nkx2.5-positive cardiomyocytes derived from murine embryonic stem cells during differentiation
HCN gene expression Nkx2.5-positive cardiomyocytes murine embryonic stem cells
2009/3/2
Changes in the expression of hyperpolarization-activated cyclic nucleotide (HCN)-gated channels and If currents during the differentiation of embryonic stem cells into cardiac cells remain unknown. ...
Rat Cardiomyocytes Express a Classical Epithelial Beta-Defensin
Innate immunity host defense peptides heart microdissection
2009/1/19
Beta-defensins (BDs) are classical epithelial antimicrobial peptides of immediate importance in innate host defense. Since recent studies have suggested that certain BDs are also expressed in non-trad...
Matrix stiffness affects spontaneous contraction of cardiomyocytes cultured within a PEGylated fibrinogen biomaterial
Cardiac cell therapy Mechanical properties Fibrin Polyethylene glycol Image analysis Hydrogel
2010/1/7
Successful implementation of cardiac cell transplantation for treating damaged myocardium relies on the development of improved
injectable biomaterials. A novel biomaterial technology using PEGylated...
Glycine protects cardiomyocytes against lethal reoxygenation injury by inhibiting mitochondrial permeability transition
reoxygenation permeability transition
2014/3/31
Post-ischaemic reperfusion may precipitate cardiomyocyte death upon correction of intra-cellular acidosis due in part to mitochondrial permeability transition. We investigated whether
glycine, an ami...