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Demographic, health, lifestyle, and blood vitamin determinants of serum total homocysteine concentrations in the third National Health and Nutrition Examination Survey, 1988–1994
creatinine smoking alcohol consumption
2016/12/30
Data from the third National Health and Nutrition Examination Survey, 1988–1994 were used to examine associations in men (n = 2965) and women (n = 3580) between tHcy and age, sex, race-ethnicity, body...
Effect of the methylenetetrahydrofolate reductase 677C→T mutation on the relations among folate intake and plasma folate and homocysteine concentrations in a general population sample
total homocysteine tHcy metabolism
2016/12/29
The objective of the study was to assess the effect of the polymorphism on the relations among folate intake, plasma folate concentration, and total plasma homocysteine (tHcy) concentration.
Homocysteine and cognitive function in healthy elderly community dwellers in Italy
Elderly subjects cognition homocysteine
2016/12/29
Fasting plasma tHcy concentrations were measured in 650 healthy, cognitively normal Italian community dwellers aged ≥ 65 y (x̅ ± SD: 72.8 ± 6.0 y). Socioeconomic status; serum folate, vitamin B-1...
Comparison of the effect of low-dose supplementation with L-5-methyltetrahydrofolate or folic acid on plasma homocysteine: a randomized placebo-controlled study
homocysteine plasma folate red blood cell folate,
2016/12/29
Food fortification with folic acid has been introduced in several countries for the prevention of neural tube defects. Fortification has lowered total homocysteine (tHcy) concentrations in the US popu...
Plasma total cysteine, pregnancy complications, and adverse pregnancy outcomes: the Hordaland Homocysteine Study
preeclampsia pregnancy outcomes total homocysteine
2016/12/29
Total homocysteine (tHcy) is associated with pregnancy complications and adverse pregnancy outcomes. The associations of plasma total cysteine (tCys) with such outcomes have not been investigated in l...
High prevalence of cobalamin deficiency in Guatemalan schoolchildren: associations with low plasma holotranscobalamin II and elevated serum methylmalonic acid and plasma homocysteine concentrations
Vitamin B-12 deficiency cobalamin deficiency methylmalonic acid
2016/12/29
Studies conducted in Guatemala, Mexico, and Venezuela have found high prevalences of low plasma cobalamin (vitamin B-12) concentrations in infants and children. It is not known whether these low cobal...
Vitamin B-12 metabolism in HIV-infected patients in the age of highly active antiretroviral therapy: role of homocysteine in assessing vitamin B-12 status
HIV vitamin B-12 folate
2016/12/29
Before the advent of highly active antiretroviral therapy (HAART), 20% and 10% of HIV-infected patients had low vitamin B-12 and red blood cell folate (RBCF) concentrations, respectively. However, few...
B vitamin status and concentrations of homocysteine and methylmalonic acid in elderly German women
women dietary intake vitamins
2017/1/4
Prior investigations found that elderly persons are at higher risk than are younger persons for B vitamin deficiency, which leads to elevated plasma total homocysteine (tHcy) concentrations that are a...
Homocysteine and cognitive function in the Sacramento Area Latino Study on Aging
folate vitamin B-12 creatinine
2017/1/4
Elevated plasma homocysteine (hyperhomocysteinemia), an independent risk factor for vascular disease, has been reported to be inversely correlated with objective measures of cognitive function in pati...
Relation between homocysteine concentrations and the consumption of different types of alcoholic beverages: the French Supplementation with Antioxidant Vitamins and Minerals Study
beer folate homocysteine
2017/1/3
Previous studies on the effects of alcohol consumption on total plasma homocysteine (tHcy) concentrations showed contradictory results. The conflicting results may derive in part from confounding by t...
Folic acid and reduction of plasma homocysteine concentrations in older adults: a dose-response study
Folic acid homocysteine dose response
2017/1/3
Elevated homocysteine concentrations, a likely risk factor for cardiovascular disease, can be lowered effectively with folic acid. The minimum dose of folic acid required for maximal reduction of homo...
Effect of protein and methionine intakes on plasma homocysteine concentrations:a 6-mo randomized controlled trial in overweight subjects
Protein methionine homocysteine diet obesity cardiovascular disease
2016/12/20
Background: A high plasma homocysteine concentration is an independent risk factor for cardiovascular disease. Homocysteine concentrations are thought to be raised by high protein and methionine ...
Contribution of caffeine to the homocysteine-raising effect of coffee:a randomized controlled trial in humans
Caffeine paper-filtered coffee homocysteine B vitamins crossover experiment
2016/12/20
Background: A high plasma total homocysteine concentration is associated with increased risk of cardiovascular disease. Consumption of unfiltered or filtered coffee raises total homocysteine conc...
Homocysteine,cardiovascular disease risk factors,and habitual diet in the French Supplementation with Antioxidant Vitamins and Minerals Study
Homocysteine habitual diet folate cardiovascular disease risk men women coffee Supplementation with Antioxident Vitamins and Minerals Study France
2016/12/20
Background: An elevated plasma total homocysteine (tHcy) concentration seems to increase the risk of cardiovascular disease.Objective: We evaluated the determinants of tHcy in healthy French...
Preconception homocysteine and B vitamin status and birth outcomes in Chinese women
Homocysteine vitamin B-12 vitamin B-6 preterm birth low birth weight pregnancy pregnancy outcome China
2016/12/20
Background: The associations between homocysteine, B vitamin status, and pregnancy outcomes have not been examined prospectively.Objective: We assessed the associations of preconception homo...