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Erratum for Traber et al. α-Tocopherol disappearance rates from plasma depend on lipid concentrations: studies using deuterium-labeled collard greens in younger and older adults. Am J Clin Nutr 2015;101:752–9
Traber plasma deuterium-labeled collard greens
2018/11/13
Erratum for Traber et al. α-Tocopherol disappearance rates from plasma depend on lipid concentrations: studies using deuterium-labeled collard greens in younger and older adults. Am J Clin Nutr 2015;1...
Determining the protein needs of “older” persons one meal at a time
protein requirement older persons
2018/11/12
The determination of protein requirements (need) and “optimal” protein intakes (greater than need but beneficial to health) is complex and currently, insofar as older persons are concerned, without co...
人冠状动脉粥样硬化病灶内CD40L水平与病灶结构变化的关系
冠状动脉粥样硬化 CD40L 基质金属蛋白酶9 病灶结构
2018/9/20
观察人冠状动脉粥样硬化病灶结构变化、CD40L、基质金属蛋白酶9(MMP-9)蛋白表达水平,探讨CD40/CD40L信号在人冠状动脉粥样硬化发生发展中的作用。 方法 收集不同程度粥样硬化的人冠状动脉血管60例作为实验组,以12例无病变的人冠状动脉为对照组,常规HE染色观察两组人群冠状动脉的组织结构并用图像分析软件检测病灶结构的相关指标,免疫组织化学染色检测CD40L、MMP-9蛋白表达水平,分析C...
研究抗衰老Klotho蛋白对过氧化氢(H2O2)氧化损伤的人脐静脉内皮细胞(HUVEC)的影响及其作用机制。 方法 用H2O2诱导HUVEC构建氧化损伤模型。将HUVEC设置对照组、H2O2损伤组、不同浓度(1、10、100 μg/L)Klotho蛋白组、丝氨酸-苏氨酸蛋白激酶(AKT)作用组。噻唑蓝法检测细胞存活率；特定试剂盒检测乳酸脱氢酶(LDH)、丙二醛(MDA)、超氧化物歧化酶(SOD)、...
Alterations in human milk leptin and insulin are associated with early changes in the infant intestinal microbiome
milk leptin insulin the infant intestinal microbiome
2018/11/12
We read with great interest the study by Lemas et al. (1) that reported early changes in the gut microbiota composition and functions of exclusively breastfed infants born from obese mothers compared ...
Breaking down, starting up: can a vitamin C–enriched gelatin supplement before exercise increase collagen synthesis?
vitamin C–enriched gelatin collagen synthesis
2018/11/12
Obesity is a major challenge to maintaining health (1) and is associated with the metabolic syndrome, whose components include diabetes, hypertension, and hypercholesterolemia (2, 3). Complications fr...
DiGeorge综合征继发自身免疫现象长期随诊1例及文献复习
DiGeorge综合征 自身免疫 血小板减少
2018/12/3
DiGeorge综合征是人类最常见的染色体微缺失疾病，常表现为先天性心脏病、甲状腺功能低下、免疫功能低下、特殊面容、腭裂及低钙血症，还可以出现发育不良、精神异常、学习能力下降、语言功能障碍等神经精神系统表现，根据患儿是否有胸腺缺失或发育不完全分为完全型和部分型两种，部分性DiGeorge综合征的免疫缺陷不明显，但容易并发自身免疫性疾病或自身免疫现象。
本文报道1例患儿出生即发现先天性心脏病、颜面...
系统性红斑狼疮并发巩膜炎4例临床分析
红斑狼疮 系统性 巩膜炎 自身免疫疾病
2018/12/3
系统性红斑狼疮（systemic lupus erythematosus，SLE）是一种全身性自身免疫病，因多种自身抗体及血管炎的存在，患者可出现多器官、系统的受累。除脑、肺、心、肾等重要脏器外，还可出现眼部病变。眼部受累表现形式多样，从眼表到眼底疾病均可出现，其中以视网膜受累最为常见，也可出现巩膜受累。广义的巩膜炎包括表层巩膜炎及巩膜炎，其作为临床上一种相对少见的眼部疾病，发病率仅占眼部疾病总数...
酷似Mikulicz病的非霍奇金淋巴瘤1例
Mikulicz病 淋巴瘤 非霍奇金 自身免疫疾病
2018/12/3
IgG4相关疾病（IgG4-related disease, IgG4-RD）是近年来逐渐被大家所认识的一种新的自身免疫病，可以累及全身多个系统，临床表现复杂多样，缺乏特异性。米库利兹病（Mikulicz disease, MD）被认为是IgG4-RD的一种亚型，有其独特的表现，包括唾液腺、泪腺、腮腺肿大，血清IgG4水平上升，腺体组织中大量IgG4+浆细胞浸润，糖皮质激素治疗有效［1］。然而，外...
Protein ingestion acutely inhibits insulin-stimulated muscle carnitine uptake in healthy young men
doubly labeled water energy requirement resting energy expenditure short bowel syndrome total energy expenditure
2018/11/26
Background: Increasing skeletal muscle carnitine content represents an appealing intervention in conditions of perturbed lipid metabolism such as obesity and type 2 diabetes but requires chronic L-car...
Habituation to low or high protein intake does not modulate basal or postprandial muscle protein synthesis rates: a randomized trial
habitual protein intake muscle protein synthesis protein digestion stable-isotope tracers whey protein
2018/11/12
Background: Muscle mass maintenance is largely regulated by basal muscle protein synthesis rates and the ability to increase muscle protein synthesis after protein ingestion. To our knowledge, no prev...
Vitamin C–enriched gelatin supplementation before intermittent activity augments collagen synthesis
bone exercise ligament tendon inury prevention return to play
2018/11/12
Background: Musculoskeletal injuries are the most common complaint in active populations. More than 50% of all injuries in sports can be classified as sprains, strains, ruptures, or breaks of musculos...
探讨载脂蛋白A5 (ApoA5)基因c.553G/T位点多态性与遵义汉族人群高胆固醇血症(HTC)的相关性。 方法 采用聚合酶链反应限制性片长多态性(PCR-RFLP)技术检测并分析101例HTC患者和118例正常对照者ApoA5基因c.553G/T位点多态性。 结果 两组中ApoA5基因 c.553G/T位点基因型频率差异有统计学意义(P<0.05),ApoA5 c.553T基因在HTC患者组中...
探讨冠心病患者血清前蛋白转化酶枯草溶菌素9(PCSK9)与小而密低密度脂蛋白胆固醇(sdLDLC)的关系。 方法 收集2014年3月至2014年12月在山西医科大学第一医院住院且行冠状动脉造影术确诊为冠心病的患者100例作为冠心病组,同期健康体检者67例作为对照组。Lipoprint脂蛋白分析仪检测LDLC颗粒大小、sdLDLC颗粒数及sdLDLC所占LDLC的百分比(简称sdLDLC百分比)；酶...
Serum 25-hydroxyvitamin D concentrations and treatment outcomes of women undergoing assisted reproduction
vitamin D infertility assisted reproductive technologies epidemiology nutrition
2018/12/14
Background: Vitamin D deficiency impairs fertility in animal models, but the role of vitamin D in human fertility or treatment of infertility is less clear.