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科学家发现IL-36通过提高IFN-α/β的敏感性以促进抗病毒免疫
IL-36 IFN-α/β 敏感性 抗病毒免疫
2019/11/13
近日,美国坦普尔大学刘易斯·卡茨医学院科研人员在Nature Communications上发表了题为“IL-36 promotes anti-viral immunity by boosting sensitivity to IFN-α/β in IRF1 dependent and independent manners”的文章,揭示了一种IL-36调节的天然免疫途径,使细胞对低水平的Ⅰ型干扰...
The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α
thymic epithelial microRNA network elevates threshold infection-associated
2012/2/1
Thymic output is a dynamic process, with high activity at birth punctuated by transient periods of involution during infection. Interferon-α (IFN-α) is a critical molecular mediator of pathogen-induce...