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A variational principle for computing nonequilibrium fluxes and potentials in genome-scale biochemical networks
Constraint-based modeling Flux balance analysis
2015/7/3
We derive a convex optimization problem on a steady-state nonequilibrium network of biochemical
reactions, with the property that energy conservation and the second law of thermodynamics both hold
a...
Robust flux balance analysis of multiscale biochemical reaction networks
reaction networks Robust flux
2015/7/3
Biological processes such as metabolism, signaling, and macromolecular synthesis can be modeled as
large networks of biochemical reactions. Large and comprehensive networks, like integrated networks ...