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α-Linolenic acid intake is not beneficially associated with 10-y risk of coronary artery disease incidence: the Zutphen Elderly Study
Coronary artery disease diet fatty acids
2016/6/14
Data on the relation between -linolenic acid
intake and coronary artery disease (CAD) are limited. Other
dietary components appear to modify the reported relation
between -linolenic acid intake and...
Dietary intake of α-linolenic acid and risk of fatal ischemic heart disease among women
Ischemic heart disease diet a-linolenic acid
2016/5/31
Experimental studies in laboratory animals and
humans suggest that a-linolenic acid (18:3n23) may reduce the
risk of arrhythmia.
Effect of dietary α-linolenic acid on thrombotic risk factors in vegetarian men
Vegetarian diet a-linolenic acid platelet fatty acid
2016/5/31
Vegetarians have lower platelet and plasma concentrations
of n23 polyunsaturated fatty acids (PUFAs) than do
omnivores. We recently showed that male vegetarians have
higher platelet aggregability t...
There are 2 series of polyunsaturated fatty acids that are
deemed essential: the n26 and n23 series. Although plants can
synthesize both the basic n26 and n23 structures, animals lack
this capacity...
Dietary -linolenic acid inhibits proinflammatory cytokine production by peripheral blood mononuclear cells in hypercholesterolemic subjects1,2,3
Hypercholesterolemic subjects -linolenic acid eicosapentaenoic acid interleukin-6
2008/12/12
Background:Atherosclerosis is a chronic inflammatory disease. We previously reported that a diet high in -linolenic acid (ALA) reduces lipid and inflammatory cardiovascular disease risk factors in hyp...
-Linolenic acid and fish oil n–3 fatty acids and cardiovascular disease risk
-Linolenic acid fish oil n–3 fatty acids cardiovascular disease risk
2008/12/12
In evaluating the cardiovascular merits of n–3 fatty acids, Wang et al (1) appropriately sought the best available evidence and used randomized controlled human trials (RCTs) as their benchmark. As th...
-Linolenic acid, 6-desaturase gene polymorphism, and the risk of nonfatal myocardial infarction1,2,3
Myocardial infarction genetics diet fatty acids epidemiology
2008/12/12
Background:6-Desaturase (FADS2) is the rate-limiting step in the polyunsaturated fatty acid (PUFA) biosynthetic pathway.Objective:The aim was to test whether the common deletion [T/-] in the promoter ...
γ-Linolenic acid supplementation for prophylaxis of atopic dermatitis—a randomized controlled trial in infants at high familial risk
Fatty acids essential fatty acids atopy
2016/12/30
In a double-blind, randomized, placebo-controlled trial, formula-fed infants (n = 118) with a maternal history of atopic disease received borage oil supplement (containing 100 mg GLA) or sunflower oil...
Dietary linolenic acid and carotid atherosclerosis: the National Heart, Lung, and Blood Institute Family Heart Study
carotid artery disease National Heart Lung
2016/12/30
Dietary intake of linolenic acid is associated with a lower risk of cardiovascular disease mortality. However, it is unknown whether linolenic acid is associated with a lower risk of carotid atheroscl...
Effects of supplementation with fish oil–derived n−3 fatty acids and γ-linolenic acid on circulating plasma lipids and fatty acid profiles in women
lasma lipids fatty
2016/12/27
Eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and γ-linolenic acid (GLA) have lipid-modifying and antiinflammatory properties. The effects of supplement mixtures of these fatty acids on pla...
Dietary linolenic acid is inversely associated with plasma triacylglycerol: the National Heart, Lung, and Blood Institute Family Heart Study
Linolenic acid cardiovascular disease risk factors
2017/1/4
Dietary intake of linolenic acid is associated with a decreased risk of cardiovascular disease mortality. However, the mechanisms by which dietary linolenic acid affects cardiovascular disease risk ar...
Effect of an increased intake of α-linolenic acid and group nutritional education on cardiovascular risk factors:the Mediterranean Alpha-linolenic Enriched Groningen Dietary Intervention (MARGARIN) study
α-Linolenic acid linoleic acid prevention ischemic heart disease nutritional education cardiovascular risk factors Netherlands MARGARIN study
2016/12/17
Background: The effect of long-term increased intakes of α-linolenic acid (ALA; 18:3n−3) on cardiovascular risk factors is unknown.Objectives: Our objectives were to assess the effect ...
A randomized trial of different ratios of linoleic to a-linolenic acid in the diet of term infants: effects on visual function and growth
a-Linolenic acid ALA linoleic acid LA, docosahexaenoic acid DHA growth visual evoked potential, VEP infants breast milk infant formula
2016/6/3
Background: There are nutritional recommendations that the
ratio of linoleic to a-linolenic acid (LA:ALA) in formula for term
infants be between 5:1 and 15:1. These recommendations were
made in the...