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Mechanism of LHRH-stimulated steroidogenesis in rat Leydig cells：lipoxygenase products of arachidonic acid may not be involved
LHRH-stimulated steroidogenesis rat Leydig cells lipoxygenase products arachidonic acid
2009/2/23
Luteinizing hormone releasing hormone agonist, [(imBzl)-DHis6,Pro9,NEt]-LHRH (LHRH-A), caused a two to threefold increase in in vitro testosterone (T) secretion by rat Leydig cells. This LHRH-A-indu...
It has been reported that Leydig cells have Fc receptors, which traditionally have been considered markers specific for macrophages and polymorphonuclear leukocytes. The purpose of this investigat...
Indomethacin and oxaprozin lower seminal prostaglandin levels but do not influence sperm motion characteristics and serum hormones of young healthy men in a placebo-controlled double-blind trial
seminal prostaglandin levels sperm motion characteristics serum hormones young healthy men
2009/2/23
To evaluate the influence of indomethacin and oxaprozin on reproductive function in healthy young men, 34 volunteers with normal semen parameters were recruited. In a randomized double-blind design,...
Induction of varicocele in the dog：I. Partial ligation of the left renal vein does not induce a varicocele in the dog
varicocele in the dog left renal vein varicocele dog
2009/2/23
Induction of varicocele was attempted by partial ligation of the left renal vein in 10 male dogs. The effects on sperm count, sperm motility, and sperm morphology, as well as on hemodynamics, were a...
Morphologic changes induced by short-term ischemia in the rat testis are not affected by treatment with superoxide dismutase and catalase
short-term ischemia rat testis superoxide dismutase and catalase
2009/2/23
Short-term testicular ischemia was induced unilaterally by ligating the testicular artery for 60 or 100 minutes in adult rats. After 7 days, the rats were fixed by vascular perfusion. The effect of ...
The effects of unilateral, experimental varicocele are not mediated through the ipsilateral testis
varicocele rat testis
2009/2/23
Unilateral varicocele has been associated with diminished male fertility in humans and with bilateral physiologic and histologic changes in the testis of humans and laboratory animals. In particul...
Epididymal fluid macromolecules do not act as auto- or alloantigens
Epididymal fluid macromolecules auto- or alloantigens
2009/2/23
Because epididymal secretory glycoproteins form important functional associations with maturing spermatozoa, the possibility has been explored that epididymal antigens might be useful in contracep...
Reproductive aging in the Brown Norway rat is characterized by accelerated germ cell apoptosis and is not altered by luteinizing hormone replacement
Brown Norway rat accelerated germ cell apoptosis luteinizing hormone replacement
2009/2/18
Reproductive aging in the male Brown Norway (BN) rat is characterized by decreased Leydig cell steroidogenesis associated with seminiferous tubule dysfunction. This could be a result of a combination ...
Suppression of growth hormone does not affect ongoing spermatogenesis in rats
Suppression of growth hormone ongoing spermatogenesis rats
2009/2/18
Recent evidence suggests that growth hormone (GH) may enhance physiologic processes, such as spermatogenesis, in addition to causing classical anabolic effects. We have previously shown that testost...
We have previously demonstrated that conditioned medium from testicular macrophages stimulates testosterone production by Leydig cells. It was also reported that conditioned medium from macrophage...
Human sperm capacitation induced by biological fluids and progesterone, but not by NADH or NADPH, is associated with the production of superoxide anion
Spermatozoa MCLA reactive oxygen species sperm hyperactivation protein tyrosine
2009/2/17
Recent evidence indicated that human sperm capacitation is associated with an increased production of superoxide anion (O2.-). To further study the role and importance of O2.- in capacitation, we in...
Gonadal and pituitary responsiveness of stallions is not down-regulated by prolonged pulsatile administration of GnRH
Equine hypothalamic-pituitary-gonadal axis ref ractoriness
2009/2/17
The objective of this study was to determine if prolonged pulsatile administration of homologous gonadotropin-releasing hormone (GnRH) at therapeutic or 5x therapeutic doses would cause down-regul...
Snow leopard（Panthera uncia）spermatozoa are sensitive to alkaline pH, but motility in vitro is not influenced by protein or energy supplements
Felid comparative biology sperm culture medium sperm function capacitation
2009/2/16
To better understand the biology of snow leopard spermatozoa and to facilitate developing assisted reproduction, a series of studies was conducted to: 1) identify the component(s) of complex cultu...
Testicular microvascular blood flow：alteration after Leydig cell eradication and ischemia but not experimental varicocele
Vasomotion testicular torsion rat
2009/2/16
Testicular microvascular blood flow is known to exhibit vasomotion, or pulsatile flow. In the present study we have used laser-Doppler flowmetry to study microvascular blood flow in the rat testis a...
Hexokinase present in human sperm is not tyrosine phosphorylated but its antibodies affect fertilizing capacity
Hexokinase human sperm fertilization infertility
2009/2/16
The present study was conducted to investigate the presence of hexokinase in human sperm cell, its subcellular localization, its modulation and role in capacitation/acrosome reaction, and tyrosine...