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Kinetic characterization of the inhibition of purified cynomolgus monkey lactate dehydrogenase isozymes by gossypol
Kinetic characterization purified cynomolgus monkey dehydrogenase isozymes gossypol
2009/2/23
This report describes the results of the first step in a sequence of experiments designed to test the hypothesis that the sperm-specific isozyme of lactate dehydrogenase (LDH-C4), is a site of actio...
Human Sertoli cells in vitro. Lactate, estradiol-17 beta and transferrin production
human Sertoli cells lactate estradioI-17ı 3 transferrin primary cultures
2009/2/11
Human Sertoli cell parameters, namely lactate, estradiol-17 beta, and transferrin production, were determined after a 24-hour incubation with either human follicle stimulating hormone (FSH) or dbcAM...
Preparation and characterization of monoclonal antibodies against sperm-specific lactate dehydrogenase C4
LDH-C4 monoclonal antibodies specificity
2009/2/6
LDH-C4, the testis-specific isozymes of lactate dehydrogenase (LDH), is the predominant LDH isozyme in mammalian spermatozoa. Nine monoclonal antibodies against mouse LDH-C4 have been developed. The...
Abundance of Repetitive Sequence Elements in the Mouse Testis-Specific Lactate Dehydrogenase-C Gene1
Isozyme restriction maps
2008/12/19
We have cloned and sequenced the entire mouse ldhc gene and mapped it physically in relation to the somatic ldha gene. The 2 genes were found to be oriented in head-to-tail fashion with about a 6-ki...
A Transgenic Analysis of Mouse Lactate Dehydrogenase c Promoter Activity in the Testis
Transcription mRNA stability protein stability
2008/12/19
Transcription of the mouse testis-specific lactate dehydrogenase c (mldhc) gene is limited to cells of the germinal epithelium. Cloning and analysis of the mldhc promoter revealed that a 100-bp co...