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Protective Effect of Silymarin on Noise-Induced Hearing Loss in Guinea Pigs
Hearing Loss Noise-Induced Silymarin Auditory Brain Stem Implantation
2015/10/9
Background: Hearing capability plays a principal role on human's communication. Noise-induced hearing loss (NIHL) caused by exposure to high noise levels is a serious socio-economic problem in modern ...
Effect of Local Nasal Immunotherapy on Nasal Blockage in Pollen-Induced Allergic Rhinitis of Guinea Pigs
allergic rhinitis animal model local nasal immunotherapy nasal blockage pollenosis
2010/11/17
Local nasal immunotherapy may be clinically useful for allergic nasal blockage associated with nasal hyperresponsiveness. The mechanisms responsible for this effectiveness might not be related to IgE ...
Effects of olopatadine hydrochloride on the release of thromboxane B2 and histamine from nasal mucosa after antigen-antibody reaction in guinea pigs
allergic rhinitis chemical mediators guinea pigs olopatadine
2010/11/25
Background: Various mediators, such as thromboxane (TX) A2, peptide leukotrienes (P-LT) and histamine, are involved in allergic nasal obstruction. The aim of the present study was to investigate the m...
Role of neutral endopeptidase in endotoxin-induced bronchial hyperresponsiveness to substance P in guinea pigs
active sensitization bronchial hyperresponsiveness endotoxin histamine neutral endopeptidase substance P
2010/11/29
To investigate effects of endotoxin on allergic airway diseases, we studied bronchial responsiveness to histamine (HI) and substance P (SP) in actively sensitized and non-sensitized guinea pigs 24 h a...