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DACS‐DB: AN ANNOTATION AND DISSEMINATION MODEL FOR DISEASE ASSOCIATED CYTOKINE SNPs
Cytokine SNP Disease
2015/5/26
Cytokines mediate crucial functions in innate and adaptive immunity. They play valuable roles in immune cell growth and lineage specification, and are associated with various disease pathologies. A la...
Structural and functional analysis of a new cytokine, ML-1 (interleukin-17F)
airway inflammation cytokine network interleukin-17 family mitogen-activated protein kinase
2010/11/24
Recent large-scale sequencing of the human genome has facilitated novel gene discovery. A novel gene, ML-1 (interleukin (IL)-17F), was identified from a human expressed sequence tag (EST) sequence, a ...
Comparison of local cytokine gene expression and the distribution of eosinophils and CD4-positive cell subsets in the paranasal sinus mucosa between atopic and non-atopic subjects
allergic rhinitis CCR4 CD4 chronic sinusitis CXCR3 cytokines eosinophils
2010/11/22
These results indicate that high expression of Th2-type cytokines concomitant with the infiltration of a predominant number of CD4+ cells and their Th2 subsets play a role in the pathogenesis of eosin...
Latex allergy in a dental nurse: Late nasal response is associated with eosinophil recruitment and T helper 2 cell type cytokine mRNA expression
eosinophils late nasal responses latex allergy T cells Th2 type cytokine
2010/11/29
The occupational uses of latex gloves may be associated with allergic rhinitis. Hypersensitivity to latex has been shown to be IgE-mediated. However, late nasal responses to latex have not been report...
Bronchial and nasal responsiveness in atopic asthma and allergic rhinitis patients: Relationship of local responsiveness to cytokine production by peripheral blood mononuclear cells
allergic rhinitis atopy bronchial asthma bronchial responsiveness interleukin-4 interleukin-5 nasal responsiveness
2010/11/29
To investigate the relationship between local responsiveness and allergic symptoms, bronchial and nasal responsiveness were measured in the following four groups of subjects: (i) bronchial asthma pati...