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DNA-Harmalol interaction: The effects of Harmalol on the solution structure of calf-thymus DNA studied by FTIR spectroscopy
Calf-thymus DNA Harmalol FTIR
2009/12/31
The interaction of hamalol with calf-thymus DNA was investigated at physiological pH with drug/DNA (phosphate) molar ratio(r) of 1/40. Fourier transform infrared difference spectroscopy were used to e...
In vivo Interaction Between Cadmium and Essential Trace Elements Copper and Zinc in Rats
Cadmium copper zinc metallothionein Cd,cadmium Cu,copper Zn,zinc MT,metallothionein
2009/6/29
H. Hakan AYDIN1 Canan ÇOKER2 Biltan ERSÖZ1 1Department of Biochemistry, Faculty of Medicine, Ege University Bornova, İzmir 35100, 2Department of Biochemistry, Faculty of Medicine, Dok...
Interaction of CpG-Oligodeoxynucleotides with Toll Like Receptor 9 Induces Apoptosis and Modulates Metaloproteinase-2 Activity in Human Intestinal Epithelium
CpG-ODN HT-29 TLR9
2010/4/20
Recent reports have indicated different effects of immunostimulatory sequences containing CpG-Oligodeoxynucleotides (ODN) on various immune cells. However, the exact role of CpG-ODN in the human gut i...
Pharmacological Interaction of Drugs with Immune Receptors: The p-i Concept
drug hypersensitivity hapten p-i concept prohapten T cells T-cell receptor
2010/11/18
Drug-induced hypersensitivity reactions have been explained by the hapten concept, according to which a small chemical compound is too small to be recognized by the immune system. Only after covalentl...
Blocking the CD154-CD40 interaction with anti-CD154 antibody differentially regulates interleukin-4 synthesis in T cells and IgE production in B cells
CD154 CD40 germline Cε IgE interleukin-4
2010/11/25
Using severe combined immunodeficiency mice engrafted with peripheral blood mononuclear cells from atopic patients, we analyzed the regulatory effects of anti-CD154 antibody on the in vivo induction o...
Differential effects of corticosteroids and theophylline on the adhesive interaction between eosinophils and endothelial cells
cell adhesion corticosteroids endothelial cells eosinophils theophyline
2010/11/22
Corticosteroids and theophylline have been used widely for the treatment of asthma. These two classes of drugs appear to reduce the tissue infiltration of eosinophils, predominant inflammatory cells i...
In vitro Glycation of Human IgG and Its Effect on Interaction with Anti-IgG
Anti-IgG Diabetes Mellitus Glycosylation Immunoglobulin G
2010/2/3
Non-enzymatic glycosylation of proteins is one of the key mechanisms in the pathogenesis of diabetic complications. Glycation of IgG is of special interest due to its possible influence on the functio...
MORPHOLOGY OF BIOMPHALARIA GLABRATA HEMOCYTES AND THEIR INTERACTION WITH MIRACIDIUM OF SHISTOSOMA MANSONI
Hemocytes Biomphalaria glabrata Schistosoma mansoni
2010/2/8
Schistosomiasis is the second most common parasitic cause of death, after malaria. Biomphalaria glabrata is a fresh water snail with medical importance since it is the intermediate host of Schistosoma...