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Extracellular vesicles (EVs), nanometer-sized messengers that travel between cells to deliver cues and cargo, are promising tools for the next generation of therapies for everything from autoimmune an...
An Anti-Aging Protein Could Be Targeted to Rejuvenate Immune Cells
Anti-Aging Protein Rejuvenate Immune Cells
2017/12/19
Anti-aging proteins have long been shown to protect against age-related diseases, such as cancer, neurodegeneration, and cardiovascular disease. A study by researchers at the Gladstone Institutes now ...
Smart molecules trigger white blood cells to become better cancer-eating machines
Smart molecules trigger blood cells cancer-eating machines
2017/10/25
A team of researchers has engineered smart protein molecules that can reprogram white blood cells to ignore a self-defense signaling mechanism that cancer cells use to survive and spread in the body. ...
Scientists have successfully regenerated cells in the retina of adult mice at the University of Washington School of Medicine in Seattle.Their results raise the hope that someday it may be possible to...
2017 B细胞和T滤泡辅助细胞 Keystone Symposia（2017 Keystone Symposia on B Cells and T Follicular Helper Cells – Controlling Long-Lived Immunity）
B Cells T Follicular Helper Cells
2017/3/7
The meeting will begin on Sunday, April 23 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, April 27 with a closing plenary sessio...
Researchers use stem cells to regenerate the external layer of a human heart
Researchers stem cells regenerate the external layer human heart
2017/2/16
A process using human stem cells can generate the cells that cover the external surface of a human heart — epicardium cells — according to a multidisciplinary team of researchers."In 2012, we discover...
Down regulation of miR-203 in radiation- induced thymic lymphoma promoted cells proliferation and inhibited apoptosis
TANK-binding kinase 1 (TBK1) SLUG (SNAI2) Cyclin D1 (CCND1)
2015/11/24
To investigate the role of miR-203 in radiation-induced thymic lymphoma (RITL).Methods A 60Co irradiator was used for total-body irradiation. MicroRNAs(miRNAs) level was assayed by qRT-PCR. Cell proli...
Increased Interleukin-17 Transcripts in Peripheral Blood Mononuclear Cells, a Link Between T-Helper 17 and Proinflammatory Responses in Bladder Cancer
Interleukin6 Interleukin17 Transforming Growth Factor Beta
2015/10/20
Background: Interleukin (IL)-17-producing CD4+ T helper (Th17) cells thatare known by producing IL-17 have recently been defined as a unique subset of proinflammatory helper cells. IL-17 is an inflamm...
天津医科大学医学免疫学课件 Immune cells and APC.
RNA Synthesis in the Tracheal Epithelial Cells of Aging Mice as Revealed by Electron Microscopic Radioautography
RNA synthesis Macromolecular Microscopic radioautography 3H-uridine
2015/7/21
For the purpose of studying the aging changes of macromolecular synthesis in the tracheal epithelial cells of experimental animals, we studied 10 groups of aging mice during development and aging from...
FUNCTIONAL GENOMICS STUDY TO UNDERSTAND THE ROLE OF SEROTONIN IN MOUSE EMBRYONIC STEM CELLS
Serotonin mouse embryonic stem cells
2015/5/26
Serotonin (5-hydroxytryptamine, 5-HT) is a monoamine neurotransmitter that is synthesized from the amino acid L-tryptophan and is reported to localize in mitochondria of embryonic stem cells. Even bef...
ROLE OF OVARIAN CANCER-INITIATING CELLS IN HIGH-GRADE SEROUS OVARIAN CARCINOGENESIS
Epigenetics DNA Methylation Carcinogenesis
2015/5/26
A subpopulation of tumor cells known as ovarian cancer initiating cells (OCICs) have been shown to be the cells that propagate the tumor phenotype in ovarian cancer. Studies have showed that a very sm...
Endothelial Colony Forming Cells (ECFCs): Identification, Specification and Modulation in Cardiovascular Diseases
Corneal endothelium Endothelial progenitor cells Arterial endothelial cell differentiation
2015/5/25
A hierarchy of endothelial colony forming cells (ECFCs) with different levels of proliferative potential has been identified in human circulating blood and blood vessels. High proliferative potential ...
IMPACT OF ALCAM (CD166) ON HOMING OF HEMATOPOIETIC STEM AND PROGENITOR CELLS
endosteal bone marrow vascular bone marrow flow cytometry
2015/5/25
The potential of hematopoietic stem cells (HSC) to home and to anchor within the bone marrow (BM) microenvironment controls the ability of transplanted HSCs to establish normal hematopoiesis. Activate...
Shp2 deletion in post-migratory neural crest cells results in impaired cardiac sympathetic innervation
Shp2 pERK Bradycardia
2015/5/25
Autonomic innervation of the heart begins in utero and continues during the neonatal phase of life. A balance between the sympathetic and parasympathetic arms of the autonomic nervous system is requir...