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Survivin promoter rs9904341 polymorphism is associated with tumor stage and grade in patients with bladder cancer
Survivin Bladder Cancer Polymorphism Apoptosis
2013/1/28
Survivin is an inhibitor of apoptosis protein and also plays a important role in the development of several malignancies. To investigate the association between survivin promoter –31 G/C (rs9904341) p...
Growth Performance of Broiler Chickens Fed Fossil Shell Growth Promoter
Fossil Shell Performance Calcium Phosphorus Broilers
2013/1/29
A study was carried out to determine the influence of fossil shell (diatomaceous earth) supplemented diets on the performance and bone composition of broiler chickens. A total of 120 day old broiler c...
Androulakis Machine learning approaches in promoter sequence analysis
Androulakis Machine learning promoter sequence analysis
2009/12/24
Gene transcription is one of the main biological processes that govern an organism's response
to external stimuli. Understanding the mechanism of gene regulation offers an avenue with
which to mode...
Association between Interleukin-10 Gene Promoter Haplotype and Schizophrenia in a Han-Chinese Study
schizophrenia IL-10 promoter region haplotypic analysis community
2009/4/14
Schizophrenia is a multi-factorial genetic disease, and it is caused by a combination of different gene polymorphisms and not individual ones, however, its pathogenesis is still unclear. The purpose o...
Androgen regulation of the human ornithine decarboxylase promoter in prostate cancer cells
Androgen receptor gene regulation
2009/2/17
We studied the response of the human ornithine decarboxylase (ODC) promoter to androgen in human prostate cancer cell lines. In the well-differentiated, androgen-sensitive human prostate cancer li...
Analysis of promoter and androgen regulatory sequences required for optimal transcription of the rat androgen-binding protein gene
Androgen-binding protein (ABP) sex hormone-binding globulin (SHBG) Sertoli cells transcriptional regulation
2009/2/17
The androgen-binding protein (ABP) gene P1 promoter directs cell-specific gene regulation of ABP secreted by Sertoli cells. A recent study using the mouse Sertoli cell line (MSC-1) with a luciferase...
Search for androgen response elements in the proximal promoter of the canine prostate arginine esterase gene
Androgenic regulation kallikreins prostate-specific antigen androgen receptor binding
2009/2/13
We have demonstrated the binding of the recombinant DNA binding domain of the rat androgen receptor to a DNA sequence of the canine prostate arginine esterase gene and have determined the functio...
目的: 构建COX-2基因启动子荧光素酶报告基因重组质粒pGL3-Basic-COX-2-promoter, 并进行功能鉴定. 方法: 根据已知人的COX-2基因启动子序列设计两端引物, 扩增人基因组DNA中的COX-2启动子. 载体质粒pGL3-Basic和COX-2启动子分别用限制性内切酶Hind Ⅲ和Bgl Ⅱ双酶切, 将COX-2基因启动子插入到pGL3-Basic报告载体中. 构建的pG...
E2F and GATA-1 are required for the Sertoli cell-specific promoter activity of the follicle-stimulating hormone receptor gene
Transcription factor testis gonadotropin
2008/12/29
The follicle-stimulating hormone receptor (FSHR) gene is expressed in Sertoli cells in males and in granulosa cells in females. Cis-acting sequences and associated binding factors responsible for ...
Recombinant Adenovirus Mediated Prostate-Specific Enzyme Pro-Drug Gene Therapy Regulated by Prostate-Specific Membrane Antigen（PSMA）Enhancer/Promoter
Cytosine deaminase prostate adenocarcinoma
2008/12/24
Gene directed enzyme pro-drug therapy (GDEPT) is one of the adjuvant therapeutic regimens for advanced prostate adenocarcinoma, and this research intended to explore how to apply targeting therapy o...
Recapitulation of Germ Cell- and Pituitary-Specific Expression With 1.6 kb of the Cystatin-Related Epididymal Spermatogenic（Cres）Gene Promoter in Transgenic Mice
Epididymis testis spermatogenesis gene regulation
2008/12/23
The Cres (cystatin-related epididymal spermatogenic) gene encodes the defining member of a new subgroup within the family 2 cystatins of cysteine protease inhibitors. Cres expression is highly tis...
Construction of Prostate-Specific Expressed Recombinant Plasmids With High Transcriptional Activity of Prostate-Specific Membrane Antigen（PSMA）Promoter/Enhancer
Adenocarcinoma regulatory element
2008/12/23
To screen different combinations of prostate-specific membrane antigen (PSMA) promoter/enhancer with the strongest transcriptional activity in prostate-specific cells, we used PSMA regulatory elemen...
A Transgenic Analysis of Mouse Lactate Dehydrogenase c Promoter Activity in the Testis
Transcription mRNA stability protein stability
2008/12/19
Transcription of the mouse testis-specific lactate dehydrogenase c (mldhc) gene is limited to cells of the germinal epithelium. Cloning and analysis of the mldhc promoter revealed that a 100-bp co...
Absence of Association Between Transforming Growth Factor–β1 Promoter Polymorphisms and Hypodontia
TGF-β1 Hypodontia Tooth agenesis
2008/12/15
Hypodontia, the congenital absence of one or a few teeth, is one of the most common alterations of the human dentition. The most common permanent missing teeth are the third molars, second premola...
Plasma UGRP1 Levels Associate with Promoter G-112A Polymorphism and the Severity of Asthma
asthma genetic polymorphism plasma levels severity uteroglobin-related protein 1
2010/11/17
The ELISA system for quantifing UGRP1 protein was established, and plasma UGRP1 levels were associated with the G-112A UGRP1 gene promoter polymorphism and the severity of asthma.