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DACS‐DB: AN ANNOTATION AND DISSEMINATION MODEL FOR DISEASE ASSOCIATED CYTOKINE SNPs
Cytokine SNP Disease
2015/5/26
Cytokines mediate crucial functions in innate and adaptive immunity. They play valuable roles in immune cell growth and lineage specification, and are associated with various disease pathologies. A la...
Endothelial Cells Are Central Orchestrators of Cytokine Amplification during Influenza Virus Infection
Endothelial Cells Central Orchestrators Cytokine Amplification
2012/2/1
Cytokine storm during viral infection is a prospective predictor of morbidity and mortality, yet the cellular sources remain undefined. Here, using genetic and chemical tools to probe functions of the...
The effect of microorganisms on cytokine secretion from bone marrow dendritic cells
Dendritic cells microorganisms cytokines
2010/10/14
Dendritic cells (DCs) are potent antigen-presenting cells crucial for initiation of cell-mediated immune responses to foreign antigens. They also contribute to the innate resistance against microbial ...
Cytokine Expression at the Inoculation Site and Nearby Tissues in an Animal Model Infected with Metacyclic Trypomastigotes of Trypanosoma cruzi
Trypanosoma cruzi American trypanosomiasis inoculation site
2010/12/10
Background. Trypanosoma cruzi infection is induced by triatomine contaminated feces containing metacyclic trypomastigotes acquired via small wounds in the skin. Natural unspecific and adaptive humoral...
Immunoregulatory Cytokine (TGF-ß And IL-10) Responses in Mice Inoculated With Protoscoleces and Major Hydatid Fluid Antigens of Cystic Echinococcosis
Echinococcus granulosus Protoscolex AgB TGF-β IL-10
2009/12/7
Background: Our objectives were to investigate whether immunomodulatory cytokines, TGF-β and IL-10, are stimulated in response to cystic echinococcosis (CE) components in mice model, and whether major...
Effects of Japanese mistletoe lectin on cytokine gene expression in human colonic carcinoma cells and in the mouse intestine
mistletoe lectin cytokine gene expression
2009/12/16
Mistletoe lectins have various biological activities including anti-cancer and immunomodulatory effects. We previously isolated a lectin (ML-J) from Japanese mistletoe. In the present study, we examin...
Polyclonal IgE Induces Mast Cell Survival and Cytokine Production
allergy antibodies cell activation human mast cells/basophils
2010/11/16
Background: Ag-dependent activation of IgE-bearing mast cells is a critical first step in immediate hypersensitivity and other allergic responses. Recent studies have revealed Ag-independent effects o...
An increasing body of evidence implicates proinflammatory cytokines in psychiatric disorders, namely, in depression. Of notice, recent studies showed that anti-inflammatory cytokines, such as IL-10, a...
CANCER GENE THERAPY USING CYTOKINE AND CHEMOKINE GENES
Adenovirus CC chemokine granulocyte macrophage-colony stimulating factor interleukin-2 retrovirus secondary lymphoid tissue chemokine
2009/7/15
Surgical or radiotherapy-mediated eradication of tumors gives the best opportunity for cure, if the tumor is restricted to the primary sites. Chemotherapy is employed for disseminated disease but freq...
Does Early Enteral Feeding Affect Clinical Outcome Or Cytokine Profiles After Elective Surgery For Colorectal Cancer?
Colorectal cancer immunonutrition cytokines
2009/6/22
Patients who have intestinal cancer are prone to malnutrition, which can result in deterioration of physiological function, poor wound healing, increased risk of infection and prolonged hospital stay....
Scalpel Versus Electrocautery Dissections: The Effect on Wound Complications and Pro-Inflammatory Cytokine Levels in Wound Fluid
Electrocautery sharp dissection seroma wound complication tumor necrosis factor-alpha interleukin-6
2009/6/16
Aim: Electrocautery has been postulated as a risk factor for wound complications. This study was conducted to evaluate the effects of electrocautery and scalpel dissections on wound complications and ...
Cytokine response after acute hyperbaric exposure in the rat
decompression dry platelet Cytokine animal rat Biological Markers Interleukin
2009/6/8
Intravascular gas has earlier been shown to activate leukocytes and platelets, enhance cell adhesion, and promote secretion of vasoactive substances from platelets. Since decompression is known to rel...
Modulation of cytokine expression by zinc and metallothionein
zinc metallothionein cytokine IL-1 IL-6 M-CSF TNF
2009/4/1
A metal chelator diethylenetriaminepentaacetic acid (DTPA) has been reported to inhibits replication of human cytomegalovirus (hCMV). In the investigation of the mechanism of DTPA-induced antiviral ef...
Dibutyltin（DBT）Dichloride Inhibits Cytokine Productions in Murine Macrophage Cell Line, J774.1.
dibutyltin macrophages tumor necrosis factor α interleukin-1β real time PCR ELISA
2009/3/23
The immune system is a target of dibutyltin (DBT) intoxication. We evaluated the effects of DBT dichloride in macrophages using the murine macrophage cell line, J774.1. Cultured J774.1 cells were expo...
Regulation of cell migration and cytokine production by HGF-like protein（HLP）/ macrophage stimulating protein（MSP）in primary microglia
cell migration cytokine production HGF-like protein
2009/3/2
HGF-like protein (HLP)/macrophage stimulating protein (MSP) is the only structural relative of hepatocyte growth factor (HGF), and is involved in the regulation of peripheral macrophage activation. ...