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Difficulties Associated with the Study of Action Potential After-potentials in Rat Cultured Sensory Neurones
Ryanodine after-potentials cultured sensory neurones apamin and niflumic acid
2009/6/29
We investigated the properties of action potential after-potentials in cultured dorsal root ganglion neurones from neonatal rats using the whole cell patch clamp technique. The aims of this study were...
Analysis of QT Prolongation Using Cardiac Action Potential Simulation
QT interval prolongation remodeling IKs current KCNE1 Luo-Rudy model
2009/6/9
In heart failure, QT interval and action potential duration (APD) is prolonged and IKs, a slow component of delayed rectifier potassium current, decreases. We have reported that the KCNE1 gene, coding...
Algorithm for multi-curve-fitting with shared parameters and a possible application in evoked compound action potential measurements
shared parameters a possible application evoked compound action potential measurements
2010/2/26
Experimental results are commonly fitted by determining parameter values of suitable mathematical expressions. In case a relation exists between different data sets, the accuracy of the parameters obt...
Action potential repolarization enabled by Ca++ channel deactivation in PSpice simulation of smooth muscle propagation
Action potential repolarization Ca++ channel deactivation smooth muscle propagation
2010/2/26
The shunt resistance across the junctions produced by the gj-channels (Rgj) was varied from 100,000 MΩ (0 gj-channels) to 10,000 MΩ (1 gj-channel), to 1,000 MΩ (10 channels), to 100 MΩ (100 channels),...
Dispersion of cardiac action potential duration and the initiation of re-entry: A computational study
cardiac action potential duration the initiation of re-entry A computational study
2010/3/1
We found a close association between increased APD dispersion and susceptibility to re-entrant arrhythmias, when APD dispersion is increased by larger spatial scale of heterogeneity, greater electroph...