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卵子向胚胎转变过程是人类繁衍后代的最重要的生命过程之一。在该过程中,人类胚胎8-细胞时期合子基因组激活之前,卵子和胚胎中DNA是不转录的。因此,卵子向胚胎转变过程主要受卵子中储存的母源mRNA调控。2023年1月17日,Nature Structural & Molecular Biology发表了题为Remodeling of maternal mRNA through poly(A) tail...
2018年2月20日,Cell Research(《细胞研究》,IF=15.6)期刊在线发表了北京大学第三医院乔杰院士与李默研究员的最新研究成果:“Poly(ADP-ribose)mediates asymmetric division of mouse oocyte”【Poly(ADP-ribose)介导小鼠卵母细胞的非对称分裂】。
Background: Burns are known as one of the most common and destructive forms of injury with a vast spectrum of consequences. Despite the discovery of various antibacterial and antiseptic agents, burn w...
研究Poly I:C诱导的肝损伤模型中肝脏内上调的CD11b + NKT细胞对CD8 +T细胞增殖反应的作用。 方法: 经腹腔注射Poly I:C(20 μg/g)制备Poly I:C诱导小鼠肝损伤模型,流式细胞术检测CD11b + NKT细胞的比例、T细胞增殖反应和CD8 +T细胞的杀伤功能,ELISA法检测细胞培养上清中的细胞因子浓度。 结果: Poly I:C诱导的肝损伤模型小鼠的肝脏中CD...
This study investigated the influence of atmospheric pressure plasma treatment on the surface properties and cell response of poly(L-lactide) (PLLA) samples. The samples were analyzed by means of X-ra...
Previously, we developed a poly(lactide-co-glycolide)/nano-hydroxyapatite (PLGA/HA) composite that overcame the limitations of conventional ceramic bone substitutes. This was achieved by introducing a...
The aim of this study was to examine the mechanical properties of a new surface-modified denture resin for its suitability as denture base material. This experimental resin is made by copolymerization...
Poly(I:C)与R848对大鼠脊髓小胶质细胞活性的影响。
The authors have examined the effects of a subcutaneous injection of the LH-RH agonist D-Trp6-LH-RH formulated in biodegradable poly(DL-lactide-co-glycolide) microcapsules on plasma levels of D-Tr...
A commercial preparation of a sodium polystyrene sulfonate (designated as N-PSS; its molecular weight is 500000 daltons) was tested as an inhibitor of sperm function and as a preventive agent for co...
期刊信息 篇名 “Poly(D,L-lactic acid) BCNU-loaded nanoparticles for the treatment of brain tumors”, 语种 英文 撰写或编译 作者 Guo Yanshuang,Chang Jin,Yuan Xu-bo(联系人) 第一作者单位 刊物名称 The second international forum on post-g...
Three strains of Azotobacter chroococcum were studied to produce poly-β hydroxybutyrate as a inclusion body by whey degradation. Optimum degradation whey results were obtained when using whey broth as...
The aim of this study is to investigate regeneration in a segmental bone defect using a novel fibrinogenbased hydrogel material. The use of hydrogels made from poly(ethylene glycol) (PEG) conjugate...

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