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Conversion of the Bifunctional 8-oxoguanine/β-δ AP DNA Repair Activities of Drosophila Ribosomal Protein S3 into the Human S3 Monofunctional β- elimination Catalyst Through a Single Amino Acid Change
DNA repair drosophila ribosomal protein s3
2014/12/12
The Drosophila S3 ribosomal protein has important roles in both protein translation and DNA repair. In regards to the latter activity, it has been shown that S3 contains vigorous N-glycosylase activit...
Lifespan Extension by the Antioxidant Curcumin in Drosophila Melanogaster
curcumin atoxdat lfespa antioxidantlifespanDrosophila
2009/4/20
The interest in health benefits associated with consumption of anti-oxidants has led to investigations examining the possibility that diets rich in anti-oxidants promote lifespan extension. Studies us...
Drosophila as a Model for Intestinal Diseases
Drosophila innate immunity intestinal stem cell
2008/12/5
Millions of people suffer diarrheal and inflammatory diseases of the intestine. Prolonged inflammation and tissue injury has also been proposed to potentiate gastrointestinal (GI) cancer. The GI tract...