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Sex- and species-dependent difference of methoxychlor O-demethylation by rat and mouse liver microsomes
sex difference species difference enantioselective metabolism cytochrome P450
2009/3/5
The in vitro metabolism of methoxychlor (MXC) and its mono-demethylated metabolites (mono-OH-MXC, including (R)- and (S)-enantiomers), was investigated using liver microsomes from rats and mice to r...