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MIT chemists have discovered the structure of a protein that can pump toxic molecules out of bacterial cells. Proteins similar to this one, which is found in E. coli, are believed to help bacteria bec...
Ateam of researchers led by Harvard and Broad Institute scientists has developed a new drug-delivery system using engineered DNA-free virus-like particles (eVLPs) that is able to edit genes associated...
Drug delivery capsule could replace injections for protein drugs（图）
药物输送胶囊 蛋白质药物 注射剂 单克隆抗体
2023/6/19
In recent years, scientists have developed monoclonal antibodies — proteins that mimic the body’s own immune defenses — that can combat a variety of diseases, including some cancers and autoimmune dis...
Bioinformatics and Pharmacogenomics in Drug Discovery and Development- a Socio-economic Perspective
U.S Human Genome Project pharmacogenomics Socio-economic
2015/5/26
A plethora of genomic and proteomic information was uncovered by the U.S Human Genome Project (HGP) – mostly by means of bioinformatics tools and techniques. Despite the impact that bioinformatics and...
The approach of exploiting highly conserved protein folds and structure in understanding protein function and in designing drugs leads to drugs that are less selective due to association with similar ...
System biology modeling : the insights for computational drug discovery
Drug Repositioning Machine Learning Side Effect
2015/5/26
Traditional treatment strategy development for diseases involves the identification of target proteins related to disease states, and the interference of these proteins with drug molecules. Computatio...
A Novel Network Biology Approach To Drug Target Selections
Network Biology Approach Drug Target Selections
2015/5/26
Conventional drug discovery focuses on single protein targets and follows a “sequence,
structure, and function” paradigm for selecting best protein targets to screen lead
chemical compounds. This es...
Bioinformatics and Pharmacogenomics in Drug Discovery and Development- a Socio-economic Perspective
bioinformatics drug development U.S Human Genome Project pharmacogenomics Socio-economic
2015/1/9
A plethora of genomic and proteomic information was uncovered by the U.S Human Genome Project (HGP) – mostly by means of bioinformatics tools and techniques. Despite the impact that bioinformatics and...