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深圳大学医学部常港副教授团队在《Nature Cell Biology》发表研究论文揭示人类精子发生过程中的全局性DNA去甲基化参与减数分裂重组的调控（图）
常港副教授 深圳大学 甲基化 精子
2023/10/23
精子发生是雄性配子产生的基础，这一发育过程受到精密调控。基因突变或表观遗传变异均能够影响精子发生，进而导致雄性不育。解析人类精子发生过程中的细胞命运调控机制，对于实现人类精子的体外再生，以及男性不育疾病的临床诊断和治疗具有重要意义。医学部常港副教授团队主要聚焦于生殖细胞发育和再生的研究。2018年，常港副教授团队联合赵小阳团队、乔杰院士团队和汤富酬团队，在世界上首次揭示了人类精子发生中的细胞命运转...
卵母细胞和早期胚胎异常是造成女性不孕及试管婴儿反复失败的重要原因。已有研究证实，遗传因素在卵母细胞和早期胚胎异常中发挥重要作用。既往研究主要集中于大家系及近亲家系患者，且致病突变主要遗传自父母，展现为显性遗传或隐性遗传模式。然而，新发突变（De novo mutations，DNMs）在卵母细胞和早期胚胎异常中发挥怎样的作用尚不清楚。
With plants as a model, studying the ‘complexity and reproducibility’ of developmental biology（图）
植物 发育生物学 分子机制
2023/7/11
Nearly paper-thin, often with a complex two-dimensional shape, leaves may number into the hundreds of thousands on an organism like a white oak. Yet typically, each leaf appears quite similar in form.
余光创课题组在《Molecular Biology and Evolution》上发表研究成果（图）
余光 创课题组 Molecular Biology and Evolution 研究成果
2019/12/11
进化生物学国际著名期刊《Molecular Biology and Evolution》(《分子生物与进化》) （1区，IF=14.797）在线发表了我校基础医学院生物信息学系余光创教授课题组的论文《treeio: an R package for phylogenetic tree input and output with richly annotated and associated dat...
同济大学生命科学与技术学院高绍荣、张勇团队研究成果发表于《Nature Cell Biology》——揭示胚胎发育异染色质修饰的重编程过程（图）
同济大学生命科学与技术学院 高绍荣 张勇 Nature Cell Biology 胚胎发育 异染色质 重编程过程
2018/5/16
2018年4月23日，我校生命科学与技术学院高绍荣教授和张勇教授课题组合作研究成果在线发表于国际权威学术期刊《Nature Cell Biology》，论文题目为“Reprogramming of H3K9me3-dependent heterochromatin during mammalian embryo development”。该文首次在全基因组水平上揭示了小鼠植入前及植入后胚胎发育过程...
2017年发育生物学高登研究研讨会（The Gordon Research Seminar on Developmental Biology）
Developmental Biology cell biology
2017/3/7
Applications for this meeting must be submitted by May 27, 2017. Please apply early, as some meetings become oversubscribed (full) before this deadline. If the meeting is oversubscribed, it will be st...
2017冷泉港亚洲会议：植物细胞和发育生物学（Cold Spring Harbor Asia conference on Plant Cell and Development Biology）
2017 冷泉港亚洲 会议 植物细胞和发育生物学
2017/2/14
We are pleased to announce the Cold Spring Harbor Asia conference on Plant Cell & Development Biology which will be held in Suzhou, China, located approximately 60 miles west of Shanghai. The conferen...
2017发育生物学戈登学术会议（The 2017 Gordon Research Conference on Developmental Biology）
2017 发育生物学戈登 学术会议
2017/2/14
Developmental Biology taps from various areas of biology (including biochemistry, cell biology, genetics, genomics, molecular biology, and evolutionary biology), as well as from physics and mathematic...
SDB is a non-profit professional society dedicated to advancement of the field of developmental biology. Over recent decades, the SDB has grown from a few hundred members to nearly 2000, and has evolv...
Experimental Standards: evaluating success in stem cell biology
experiment stem cells epistemic history
2011/9/5
This paper aims to bring the epistemic dimensions of stem cell experiments out of the background, and show that they can be critically evaluated. After introducing some basic concepts of stem cell bio...