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Effect of fructose consumption on insulin sensitivity in nondiabetic subjects: a systematic review and meta-analysis of diet-intervention trials
fructose glucose clamp glucose disposal insulin insulin resistance meta-analysis
2018/12/19
Background: High fructose consumption has been suggested to contribute to several features of metabolic syndrome including insulin resistance, but to our knowledge, no previous meta-analyses have inve...
Anabolic sensitivity of postprandial muscle protein synthesis to the ingestion of a protein-dense food is reduced in overweight and obese young adults
insulin resistance leucine muscle mass inflammation amino acid transporters mTORC1
2018/12/14
Background: Excess body fat diminishes muscle protein synthesis rates in response to hyperinsulinemic-hyperaminoacidemic clamps. However, muscle protein synthetic responses after the ingestion of a pr...
Anabolic sensitivity of postprandial muscle protein synthesis to the ingestion of a protein-dense food is reduced in overweight and obese young adults
insulin resistance leucine muscle mass inflammation amino acid transporters mTORC1
2018/12/18
Background: Excess body fat diminishes muscle protein synthesis rates in response to hyperinsulinemic-hyperaminoacidemic clamps. However, muscle protein synthetic responses after the ingestion of a pr...
Insulin sensitivity is a Rubik’s Cube
Insulin sensitivity complex metabolic exercise diet
2018/11/30
Insulin sensitivity is determined by complex metabolic interactions dictated by a multitude of inputs that include inherited genetic and epigenetic determinants as well as many varying modifiers such ...
Combined epigallocatechin-3-gallate and resveratrol supplementation for 12 wk increases mitochondrial capacity and fat oxidation, but not insulin sensitivity, in obese humans: a randomized controlled trial
insulin sensitivity mitochondrial capacity obesity polyphenols resveratrol
2018/12/3
Background: The obese insulin-resistant state is characterized by impairments in lipid metabolism. We previously showed that 3-d supplementation of combined epigallocatechin-3-gallate and resveratrol ...
The Effects of Chromium on Skeletal Muscle Membrane/Cytoskeletal Parameters and Insulin Sensitivity
Cholesterol Actin Skeletal muscle
2015/5/22
A recent review of randomized controlled trials found that trivalent chromium (Cr3+) supplementation significantly improved glycemia among patients with diabetes, consistent with a long-standing appre...
Afferent nerve sensitivity is decreased by an iNOSdependent mechanism during indomethacin-induced inflammation in the murine jejunum in vitro
inflammatory bowel disease intestinal inflammation nitric oxide visceral sensitivity
2014/5/16
Evidence exists that visceral afferent sensitivity is subject to regulatory mechanisms. We hypothesized that afferent sensitivity is decreased in the small intestine during intestinal inflammation by ...
Vagal modulation of intestinal afferent sensitivity to systemic LPS in the rat
autonomic innervation electrophysiology mesenteric vagus nerve visceral hypersensitivity lipopolysaccharide
2014/5/16
Liu CY, Mueller MH, Grundy D, Kreis ME. Vagal modulation of intestinal afferent sensitivity to systemic LPS in the rat. Am J Physiol Gastrointest Liver Physiol 292: G1213–G1220, 2007. First published ...
Diabetes and Myocardial Ischaemia-Sensitivity of the diabetic heart to ischemic injury
Diabetes Myocardial Ischaemia-Sensitivity diabetic heart
2014/3/31
Tani M,Neely JR. Hearts from diabetic rats are more resistant to in vitro ischemia. Possible role of altered calcium metabolism. Circ Res 1988, 62:931-940.