搜索结果: 1-5 共查到“酶学 Catalysis”相关记录5条 . 查询时间(0.082 秒)
近日,上海交通大学系统生物医学研究院达林泰课题组和张延课题组在生物化学领域著名期刊《ACS Catalysis》联合发表了题为 “Regulatory Role of One Critical Catalytic Loop of Polypeptide N-Acetyl Galactosaminyltransferase-2 in Substrate Binding and Catalysis d...
近日,我校生物反应器工程国家重点实验室及上海生物制造技术协同创新中心许建和课题组,在改变羟甾脱氢酶辅酶偏好性方面研究取得新突破。美国化学会催化杂志(ACS Catalysis)以“Switching cofactor dependence of 7β-Hydroxysteroid dehydrogenase for cost-effective production of ursodeoxycho...
ACS Catalysis报道华东理工大学酶结构重塑研究的新成果(图)
酶结构重塑 胺脱氢酶 酮胺化还原酶
2018/3/13
近日,我校生物工程学院生物反应器工程国家重点实验室及上海生物制造技术协同创新中心许建和课题组,在胺脱氢酶/酮胺化还原酶的结构重塑和功能拓展方面研究取得新突破。美国化学会催化杂志ACS Catalysis以“Reshaping the Active Pocket of Amine Dehydrogenases for Asymmetric Synthesis of Bulky Aliphatic A...
近日,华东理工大学生物反应器工程国家重点实验室在高活性羰基还原酶的理性改造与合成应用方面取得可喜进展。美国化学会期刊ACS Catalysis以“Preparation of Structurally Diverse Chiral Alcohols by Engineering Ketoreductase CgKR1”(ACS Catal.2017, DOI:10.1021/acscatal.7b...
Evaluation of the Energetics of the Concerted Acid-Base Mechanism in Enzymatic Catalysis:The Case of Ketosteroid Isomerase
Energetics Concerted Acid-Base Mechanism Enzymatic Catalysis Ketosteroid Isomerase
2016/5/25
Structures of enzymes invariably reveal the proximity of acidic and basic residues to reactive sites on the substrate, so it is natural and common to suggest that enzymes employ concerted mechanisms t...