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Computational Studies of the Structural Stability of Rabbit Prion Protein Compared to Human and Mouse Prion Proteins
Neurodegenerative Diseases Prion Diseases Immunity Rabbit Prion Protein Rabbit NMR X-ray and Homology Structures
2011/8/11
Abstract: Prion diseases are invariably fatal and highly infectious neurodegenerative diseases affecting humans and animals. The neurodegenerative diseases such as Creutzfeldt-Jakob disease, variant C...
Formation and Stability of Synaptic Receptor Domains
Formation Stability Synaptic Receptor Domains
2011/1/5
Neurotransmitter receptor molecules, concentrated in postsynaptic domains along with scaffold and a number of other molecules, are key regulators of signal transmission across synapses. Employing expe...
Rho small GTPase regulates the stability of individual focal adhesions: a FRET-based visualization of GDP/GTP exchange on small GTPases
cell motility cell-substratum adhesion Rac
2010/12/2
RhoA and Rac1 are small GTPases primarily involved in cytoskeletal remodeling. Many biochemical studies have suggested that they are also key organizers of cell-substrate adhesion. Recently, fluoresce...