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Sensitivity analysis of a computational model of the IKK-NF-κB-IκBα-A20 signal transduction network
Sensitivity analysis computational model IKK-NF-κB-IκBα-A20 signal transduction
2010/11/15
The NF-{\kappa}B signaling network plays an important role in many different compartments of the immune system during immune activation. Using a computational model of the NF-{\kappa}B signaling netw...
Improved Network Performance via Antagonism: From Synthetic Rescues to Multi-drug Combinations
Network Performance Multi-drug Combinations
2010/4/6
Recent research shows that a faulty or sub-optimally operating metabolic network can often be rescued by the targeted removal of enzyme-coding genes--the exact opposite of what traditional gene therap...