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What if, in people with blinding retinal disorders, one could simply introduce into the retina healthy photoreceptor cells derived in a dish from stem cells, and restore sight?
Terence D. Capellini has been interested in how joints work for almost three decades. Part of it is due to personal experience, as he suffered several joint injuries as a college ice hockey player and...
Numerous studies have shown that trained dogs can detect many kinds of disease — including lung, breast, ovarian, bladder, and prostate cancers, and possibly Covid-19 — simply through smell. In some ...
Researchers wirelessly manipulate gene, step toward reprogramming the human genome（图）
manipulate gene toward reprogramming human genome
2019/10/23
A new University at Buffalo-led study supported by NSF describes how researchers wirelessly controlled FGFR1 -- a gene that plays a key role in how animals grow from embryos to adults -- in lab-grown ...
Study illuminates fate of marine carbon in last steps toward sequestration
fate marine carbon last steps toward sequestration
2017/7/20
The ocean sequesters massive amounts of carbon in the form of “dissolved organic matter,” and new research explains how an ancient group of cells in the dark ocean wrings the last bit of energy from c...
Spatially Selective Manipulation of Supported Bilayers by Laminar Flow:Steps Toward Biomembrane Microfluidics
chimeric plasmid interleukin-4 interleukin-10 poly[alpha-(4-aminobutyl)-L-glycolic acid] (PAGA) type I diabetes
2016/5/24
The ability to manipulate supported lipid bilayers after formation on a substrate has made possible new classes of both molecular and cellular level experiments. In this report, we combine the unique ...
Measuring the health of the Chesapeake Bay: toward integration and prediction
health of the Chesapeake Bay integration prediction
2016/5/19
Measuring the health of the Chesapeake Bay: toward integration and prediction.
Toward an antibody peptidase: Mechanistic studies of peptide-bond hydrolysis
Antibody peptide enzyme hydrolysis peptide peptide bond hydrolysis temperature primary amine derivatives
2014/12/11
To maximize the probability of obtaining an antibody peptidase, an efficient assay for the hydrolysis of peptide bonds was developed. Two methods for detecting the uncatalyzed rate of hydrolysis of a ...
Toward an understanding of the role of the L1 stalk in translocation by the Escherichia coli ribosome
Ribosomes the extension of cyclic code metastable state catalytic interactive translocation protein
2014/12/11
Translocation is the process by which the ribosome advances the mRNA:tRNA complex by a one-codon step during the elongation cycle of translation. In the pre-translocation state, the ribosome transitio...
Toward an understanding of the role of the L1 stalk in translocation by the Escherichia coli ribosome
Biological sciences Hybrid state L1 Ribosome rRNA Translocation
2014/12/10
Translocation is the process by which the ribosome advances the mRNA:tRNA complex by a one-codon step during the elongation cycle of translation. In the pretranslocation state, the ribosome transition...
Role of a putative bacterial lipoprotein in Pseudomonas aeruginosa-mediated cytotoxicity toward airway cells
Pseudomonas aeruginosa infection Cystic Fibrosis Cytotoxicity
2015/5/22
The patients with Cystic fibrosis (CF), an inherent genetic disorder, suffer from chronic bacterial infection in the lung. In CF, modification of epithelial cells leads to alteration of the lung envir...
Theoretical and computational tools that can be used in the clinic to predict neoplastic progression and propose individualized optimal treatment strategies to control cancer growth is desired. To dev...
Systems Biology-Toward System-level Understanding of Biological Systems
Systems Biology-Toward System-level
2014/3/31
System Design: the strategies to modify and construct biological systems having desired properties can be devised based on definite design principles and simulations, instead of blind trial-and-error.