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开花途径关键转录因子CO（CONSTANS）是植物响应光周期信号诱导开花过程的关键决定因子之一。在长日照（LD）条件下，植物幼叶维管组织韧皮部中的CO蛋白结合成花素基因FT的启动子，从而激活FT基因的表达，促进植物开花过程。此外，CO基因还在植物嫩叶叶肉细胞和根部等多个组织中表达，而相应的生物学功能及其分子机制研究甚少。
中国科学院研究揭示CO蛋白参与茉莉酸激素信号昼夜节律性调控（图）
CO蛋白 茉莉酸激素
2022/12/5
CO（CONSTANS）转录因子是植物光周期和生物钟信号途径调控开花过程的关键决定因子之一，是植物学家长期以来关注和研究的“明星”蛋白。在长日照条件下，CO能直接激活FT基因的表达，从而促进植物开花过程。CO基因除了在幼叶微管组织中表达诱导开花，还可以在幼叶的叶肉细胞以及根部强烈表达。然而，幼叶的叶肉细胞以及根部表达的CO的重要生物学功能，未见报道。
CO（CONSTANS）转录因子是植物光周期和生物钟信号途径调控开花过程的关键决定因子之一，是植物学家长期以来关注和研究的“明星”蛋白。在长日照条件下，CO能直接激活FT基因的表达，从而促进植物开花过程。有趣的是，CO基因除了在幼叶微管组织中表达诱导开花，还可以在幼叶的叶肉细胞以及根部强烈表达。但是，幼叶的叶肉细胞以及根部表达的CO具有什么重要生物学功能呢？到目前为止，尚未见相关研究报道。
Dynamics of Myoglobin-CO with the Proximal Histidine Removed:Vibrational Echo Experiments
Myoglobin-CO Proximal Histidine Removed Vibrational Echo Experiments
2016/5/23
Picosecond infrared vibrational echo measurements from 60 to 300 K on CO bound to the active site of a mutant myoglobin, H93G(N-MeIm), are presented and compared to measurements on native myoglobin an...
Modulation of Protein Function by Exogenous Ligands in Protein Cavities:CO Binding to a Myoglobin Cavity Mutant Containing Unnatural Proximal Ligands
Animals Binding Sites Carbon Monoxide Cloning, Molecular Escherichia coli Heme Kinetics Ligands Magnetic Resonance Spectroscopy Mutagenesis, Site-Directed Myoglobin Myoglobin Point Mutation Protein Conformation ecombinant Proteins Recombinant Proteins Spectroscopy,Fourier Transform Infrared Valine Whales
2016/5/23
A variety of heterocyclic ligands can be exchanged into the proximal cavity of sperm whale myoglobin mutant H93G, providing a simple method for introduction of the equivalent of unnatural amino acid s...
A Test of the Role of Electrostatic Interactions in Determining the CO Stretch Frequency in Carbonmonoxymyoglobin
Electrochemistry Escherichia coli Humans Mutagenesis, Site-Directed Myoglobin Point Mutation Protein Conformation Recombinant Proteins Spectroscopy, Fourier Transform Infrared Vibration
2016/5/23
The vibrational frequency of CO bound to myoglobin can be varied by up to 60 cm-1 by making site-specific mutations in the distal pocket. These changes may result from specific chemical interactions b...
Perturbations of the Distal Heme Pocket in Human Myoglobin Mutants Probed by Infrared Spectroscopy of Bound CO:Correlation with Ligand Binding Kinetics
Distal Heme Pocket Human Myoglobin Mutants Probed Infrared Spectroscopy Bound CO:Correlation Ligand Binding Kinetics
2016/5/23
The infrared spectra of CO bound to human myoglobin and myoglobin mutants at positions His-64, Val-68, Asp-60, and Lys-45 on the distal side have been measured between 100 and 300 K. Large differences...
CO Recombination to Human Myoglobin Mutants in Glycerol-Water Solutions
CO Recombination Human Myoglobin Mutants Glycerol-Water Solutions
2016/5/23
The kinetics of CO recombination to site-specific mutants of human myoglobin have been studied by flash photolysis in the temperature range 250-320 K on the nanosecond to second time scale in 75% glyc...
Protein evolution in two co-occurring types of Symbiodinium: an exploration into the genetic basis of thermal tolerance in Symbiodinium clade D
Symbiodinium Thermal tolerance Coral
2015/12/11
The symbiosis between reef-building corals and photosynthetic dinoflagellates (Symbiodinium) is an
integral part of the coral reef ecosystem, as corals are dependent on Symbiodinium for the majority ...
Activity time budget patterns of sheep and goats co-grazing on semi-natural species-rich dry grassland
animal behaviour activity pattern small ruminant mixed pasture semi-natural grassland
2015/6/24
Activity time budget patterns and grazing response to sward and environmental conditions were investigated for paddocks of sheep and goats co-grazing for conservation purposes on a semi-natural specie...
Genetic Study of ‘Co-Evolution’Could Provide Clues to Better Food Production
Genetic Study Co-Evolution Provide Clues Better Food Production
2015/7/13
In 1964, renowned biologists Peter Raven and Paul Erhlich published a landmark study that introduced the concept of co-evolution. Using butterflies and plants as primary examples, the team deter...
利用16S rDNA基因及线粒体DNA细胞色素氧化酶亚基Ⅰ（cytochrome oxidase subunit I gene，COⅠ）基因建立3种形态学特征相近的血蜱属蜱类-长角血蜱、褐黄血蜱及铃头血蜱的分子生物学鉴定方法，探讨它们的系统发生关系。 方法 在上海市动物体表采集寄生蜱，在解剖显微镜下进行形态学鉴定后，提取蜱样本基因组DNA，采用PCR方法从蜱基因组中扩增16S rDNA及COⅠ基因...
Site Characteristics and Plant Invasion: Light Limitation of Invasive Establishment and Impacts of Elaeagnus Umbellata on Soil Nitrogen Availability and Co-occurring Species
soil nitrogen invasion facilitation
2015/1/6
Invasive species have become an increasing threat to many habitats worldwide. This research addressed the questions of whether several invasive woody plants can germinate, survive and grow in light le...
Investigations of glycoprotein co-translational maturation in the cell
New protein Protein Endoplasmic reticulum cavity Protein folding Coupling molecules Fold the sensor Membrane glycoprotein
2014/12/11
The earliest steps of nascent protein folding are critical to the overall folding efficiency. Folding events start as soon as the protein is translocated into the endoplasmic reticulum lumen, where th...
WC1 Functions as a Co-Receptor and A Pattern Recognition Receptor In Bovine Gamma delta T Cells
Health and environmental sciences Endocytosis Gamma delta t cells Receptor-ligand interactions Wc1 Pattern recognition receptors
2014/12/10
WC1 proteins specifically expressed on the surface of γδ T cells are members of group B Scavenger Receptor Cysteine Rich (SRCR) superfamily, in which receptors contain several SRCR domains in the extr...