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Robustness of an Odds-ratio Test in a Stratified Group Sequential Trial with a Binary Outcome Measure
Binary outcome Odds-ratio Stratification
2015/3/18
Many clinical trials compare two or more treatment groups by using a binary outcome measure.
For example, the goal could be to determine whether the frequency of pain episodes is
significantly reduc...
In the conviction of Lucia de Berk an important role was played by a simple hypergeometric model, used by the expert consulted by the court, which produced very small probabilities of occurrences of c...