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In response to glucose, pancreatic islet beta cells secrete insulin in a biphasic manner, and both phases are diminished in type 2 diabetes. In beta cells, cortical F-actin beneath the plasma membrane...
Modeling of the gap junction of pancreatic β-cells and the robustness of insulin secretion
pancreatic β-cells gap junctions synchronization robustness
2010/12/2
Pancreatic β-cells are interconnected by gap junctions, which allow small molecules to pass from cell to cell. In spite of the importance of the gap junctions in cellular communication, modeling studi...