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南京农业大学农学院《Nature Communications》发表万建民院士团队“Genome-Wide association studies identify OsWRKY53 as s key regulator of salt tolerance in rice”（图）
万建民 基因 分子机制 蛋白
2023/10/28
盐碱胁迫影响水稻的生长发育、存活率与最终产量。水稻耐盐碱是由多基因控制的复杂性状。研究水稻应对盐碱胁迫的关键基因及其调控网络，对于培育耐盐碱水稻品种具有重要科学意义和应用价值。2023年6月16日，国际著名期刊Nature Communications发表了万建民院士团队在水稻耐盐碱研究上的新进展。
The liver’s ability to regenerate itself is legendary. Even if more than 70 percent of the organ is removed, the remaining tissue can regrow an entire new liver.
In Down syndrome cells, genome-wide disruptions mimic a senescence-like state（图）
唐氏综合症 细胞生物学 全基因组 破坏模仿 衰老样状态
2023/6/6
In Down syndrome, the third copy of chromosome 21 causes a reorganization of the 3D configuration of the entire genome in a key cell type of the developing brain, a new study shows. The resulting disr...
Genome-wide identification of NF-YA gene family in cotton and the positive role of GhNF-YA10 and GhNF-YA23 in salt tolerance
全基因组分析 雷蒙德氏棉 亚洲棉 海岛棉 陆地棉
2024/5/17
本研究基于全基因组分析，在雷蒙德氏棉、亚洲棉、海岛棉和陆地棉基因组中分别鉴定得到16、16、31和29个NF-YA基因。通过进化树分析将NF-YA基因分为4个亚组。结构分析表明NF-YA基因在棉属进化过程中相对保守。荧光定量显示GhNF-YAs可能通过ABA和 MeJA的调控通路响应盐和干旱。VIGS沉默GhNF-YA10和GhNF-YA23的表达，能显著降低棉花对盐的抗性，表明这两个基...
Genome-wide polymorphisms show unexpected targets of natural selection
population genomics natural selection
2015/12/11
Natural selection can act on all the expressed genes of an individual, leaving signatures of genetic differeniation or diversity at many loci across the genome. New power to assay these genome-wide ef...
Genome-wide Association Study to Identify Quantitative Trait Loci for Meat and Carcass Quality Traits in Berkshire
Berkshire Quantitative Trait Loci Single Nucleotide Polymorphism Meat Quality
2016/5/19
Meat and carcass quality attributes are of crucial importance influencing consumer preference and profitability in the pork industry. A set of 400 Berkshire pigs were collected from Dasan breeding far...
A Genome-wide Scan for Selective Sweeps in Racing Horses
Single Nucleotide Polymorphism Racehorse Selective Sweep Quantitative Trait Loci
2016/5/19
Using next-generation sequencing, we conducted a genome-wide scan of selective sweeps associated with selection toward genetic improvement in Thoroughbreds. We investigated potential phenotypic conseq...
Stories and Challenges of Genome Wide Association Studies in Livestock — A Review
QTL Livestock Genome-wide Association
2016/5/18
Undoubtedly livestock is one of the major contributors to the economy of any country. The economic value of livestock includes meat, dairy products, fiber, fertilizer etc. Understanding and identifyin...
Multiple Genes Related to Muscle Identified through a Joint Analysis of a Two-stage Genome-wide Association Study for Racing Performance of 1,156 Thoroughbreds
Single Nucleotide Polymorphism Estimated Breeding Value
2016/5/18
Thoroughbred, a relatively recent horse breed, is best known for its use in horse racing. Although myostatin (MSTN) variants have been reported to be highly associated with horse racing performance, t...
Genome-Wide Identifi cation of MicroRNAs inMedicago truncatula by High-Throughput Sequencing
microRNA Medicago truncatula High-throughput sequencing Bioinformatics analysis
2015/2/5
MicroRNAs (miRNAs) are small, endogenous RNAs that play important regulatory roles in development and stress response in plants by negatively regulating gene expression post-transcriptionally.Medicago...
Identification of aluminum-responsive microRNAs in Medicago truncatula by genome-wide high-throughput sequencing
Aluminum toxicity High-throughput sequencing Medicago MicroRNA
2015/2/5
MicroRNAs (miRNAs) play important roles in response of plants to biotic and abiotic stresses. Aluminum (Al) toxicity is a major factor limiting plant growth in acidic soils. However, there has been li...
Identification of drought-responsive microRNAs in Medicago truncatula by genome-wide highthroughput sequencing
drought-responsive microRNAs Medicago truncatula genome-wide highthroughput sequencing
2015/2/5
Backg round: MicroRNAs (miRNAs) are small, endogenous RNAs that play important regulatory roles in development and stress response in plants by negatively affecting gene expression post-transcriptiona...
Genome-wide analysis for native thyroid hormone targets in developing brain and mechanisms of endocrine disruption at the thyroid hormone receptor
Thyroid hormone fetal brain development interference and signal brain development polychlorinated biphenyls (PCBS)
2014/12/11
Thyroid hormone (TH) plays an important role in fetal brain development. Therefore, exogenous factors that interfere with TH signaling may exert potentially important adverse effects on brain developm...
Genetic loci associated with circulating phospholipid trans fatty acids: a meta-analysis of genome-wide association studies from the CHARGE Consortium
arachidonic acid genome-wide association meta-analysis phospholipid trans fatty acids
2018/12/20
Background: Circulating trans fatty acids (TFAs), which cannot be synthesized by humans, are linked to adverse health outcomes. Although TFAs are obtained from diet, little is known about subsequent i...
A Genome Wide Association Study on Age at First Calving Using High Density Single Nucleotide Polymorphism Chips in Hanwoo (Bos taurus coreanae)
Single Nucleotide Polymorphism Whole Genome
2016/5/17
Age at first calving is an important trait for achieving earlier reproductive performance. To detect quantitative trait loci (QTL) for reproductive traits, a genome wide association study was conducte...