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Next-generation DNA sequencing identifies novel gene variants and pathways involved in specific language impairment
ERC1 GRIN2A SRPX2
2017/8/25
A significant proportion of children have unexplained problems acquiring proficient linguistic skills despite adequate intelligence and opportunity. Developmental language disorders are highly heritab...
A common variant of the CNTNAP2 gene is associated with structural variation in the left superior occipital gyrus
CNTNAP2 Dorsal visual stream FOXP2 Grey matter Language VBM
2016/5/3
The CNTNAP2 gene encodes a cell-adhesion molecule that influences the properties of neural networks and the morphology and density of neurons and glial cells. Previous studies have shown association o...
Meta-analysis of gene–environment-wide association scans accounting for education level identifies additional loci for refractive error
Meta-analysis gene environment wide association scans accounting education level identifies additional loci refractive error
2016/5/3
Myopia is the most common human eye disorder and it results from complex genetic and environmental causes. The rapidly increasing prevalence of myopia poses a major public health challenge. Here, the ...
Early developmental gene enhancers affect subcortical volumes in the adult human brain
functional genomics gene enhancer GWAS hippocampus neurodevelopment subcortical volume
2016/5/3
Genome-wide association screens aim to identify common genetic variants contributing to the phenotypic variability of complex traits, such as human height or brain morphology. The identified genetic v...
Lateralization of gene expression in human language cortex
Lateralization Gene expression
2015/12/18
Lateralization is an important aspect of the functional brain architecture for language and
other cognitive faculties. The molecular genetic basis of human brain lateralization is
unknown, and recen...