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Localization of 3-phosphoglycerate dehydrogenase, an enzyme involved in de novo L-serine biosynthesis, in the peripheral nervous system and non-neuronal tissues of mice
3-phosphoglycerate dehydrogenase novo L-serine biosynthesis peripheral nervous system
2009/3/3
The non-essential amino acid L-serine is biosynthesized from 3-phosphoglycerate by astrocytes, and functions as a key mediator of neurotrophic support in the brain. In the present study, the cellula...