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Identification, kinetic and structural characterization of small molecule inhibitors of aldehyde dehydrogenase 3a1 (Aldh3a1) as an adjuvant therapy for reversing cancer chemo-resistance
cyclophosphamide chemosensitivity structure activity relationships cell culture
2015/5/25
ALDH isoenzymes are known to impact the sensitivity of certain neoplastic cells toward cyclophosphamides and its analogs. Despite its bone marrow toxicity, cyclophos-phamide is still used to treat var...
Patients with resected colon cancer (stage III [T1 to T4, N1-N2] or high-risk stage II [T3 or T4, N0]) or stage II/III rectal cancers (T3 or T4, N0-2) are at significant risk of local and distant fail...
Intramuscular diclofenac sodium as adjuvant therapy for type I decompression sickness: a case report
decompression sickness human case report diclofenac sodium drug adjunctive therapy nonsteroidal anti-inflammatory drug NSAID
2009/7/14
The residual pain of type I decompression sickness (limb bends) occurring despite recompression therapy is due to an acute inflammatory reaction in the soft tissue around the joint. This case history ...
Lignocaine and Non-Steroidal Anti-Inflammatory Drugs as adjuvant therapy in treating decompression illness
Decompression illness drugs treatment
2009/5/25
Simon Mitchell has reviewed the evidence
supporting the use of lignocaine, an aminoethylamide local
anaesthetic with class 1B anti-arrhythmic properties, as
adjuvant therapy to the accepted modalit...
Adjuvant therapy for decompression illness
Accidents decompression illness drugs treatment
2009/5/25
The definitive treatment of DCI is administration of
oxygen in a recompression chamber. However, in
recreational diving a chamber is rarely available on site,
often necessitating delays of several ...
Intraoperative Ethanol Treatment as an Adjuvant Therapy of Pterygium Excision
ethanol excision pterygium recurrence mitomycin
2009/4/20
Recurrence of pterygium is the main concern for ophthalmic surgeons after the excision of pterygium. To evaluate the efficacy and safety of ethanol treatment during pterygium excision in preventing t...