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In vivo and in vitro induction of cytochrome P-450 synthesis in hyperoxia
animal mice Cytochrome P-450 Dark Adaptation Light Adaptation
2009/7/17
Exposure of dark- or light-adapted mice to 1--3 ATA oxygen for times ranging from 15 min to 4 h caused a progressive increase in P-450, which peaked and then decayed. The rate of decay appears to be i...
Synthesis of cytochrome P-450 in isolated liver cells during exposure to hyperoxia
animal mice cytochrome P-450 liver
2009/7/15
Mouse hepatocytes were separated within 15 min of the death of the animal. A method of determining cytochrome P-450 was developed and used to show that cells prepared quickly still contained normal le...