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Deletion of the Lmna Gene Induces Growth Delay and Serum Biochemical Changes in C57BL/6 Mice
Lmna Deficient Mice Growth Delay Serological Changes
2016/5/16
The A-type lamin deficient mouse line (Lmna−/−) has become one of the most frequently used models for providing insights into many different aspects of A-type lamin function. To elucidate ...
Scientists from USC and NYU design a molecule that blocks cancer growth in mice
Scientists from USC NYU design a molecule blocks cancer growth in mice
2014/6/12
A team of researchers from USC and NYU has developed and patented a small molecule that interferes with cancer progression with minimal side effects.
The molecule prevents two critical proteins from ...
Mice give ticks a free lunch-Amplifying Risk of Lyme Disease and Other Tick-Borne Ailments
Mice free lunch Risk of Lyme Disease Other Tick-Borne Ailments
2014/3/28
(Millbrook, NY) People living in northern and central parts of the U.S. are more likely to contract Lyme disease and other tick-borne ailments when white-footed mice are abundant. Mice are effective a...
Immune system drives pregnancy complications after fetal surgery in mice（图）
Immune system drives pregnancy complications
2014/3/18
As a fetal surgeon at UC San Francisco, Tippi MacKenzie, MD, has long known that conducting surgery on a fetus to correct a problems such as spina bifida often results in preterm labor and premature b...
Toxoplasmosis:Experimental Vaginal Infection in NMRI Mice and Its Effect on Uterin, Placenta and Fetus Tissues
Infection Toxoplasma Vaginal NMRI Mice
2015/10/8
Background: Toxoplasma gondii is an important zoonotic pathogen. Vertical transmission of the parasite occurs when females were infected primarily during gestation. This parasite is transmitted to the...
Influenza Virus-like Particle Containing Two Different Subtypes of Hemagglutinin Confers Protection in Mice Against Lethal Challenge With A/PR8 (H1N1) and A/HK (H3N2) Viruses
Orthomyxoviridae Virus-like particles Influenza Vaccines
2015/9/29
Background: Preventing the seasonal or pandemic outbreak of influenza can be powerful and cost-effective.
Metabolic Adaptations in the Liver of Born Long-Distance Running Mice
PPAR DELTA SIRTUIN 1 LIVER METABOLISM GLUCONEOGENESIS, LIPOGENESIS
2017/7/17
Purpose: Long-distance runners have increased needs of energy supply. To unravel genetically based mechanisms required for efficient energy supply, we have analyzed hepatic metabolism of mice characte...
Effect of Beta-Alanine and Carnosine Supplementation on Muscle Contractility in Mice
ANSERINE FATIGUE RESISTANCE FORCE–FREQUENCY RELATION CALCIUM HANDLING
2017/7/14
Purpose: Enhanced carnosine levels have been shown to be ergogenic for high-intensity exercise performances, although the role of carnosine in the control of muscle function is poorly understood. Ther...
Synergistic effects of Isatis tinctoria L. and tacrolimus in the prevention of acute heart rejection in mice
satis tinctoria L mice
2013/6/26
Although immunosuppressive treatments are available for acute cardiac rejection no viable treatment exists for long-term cardiac graft failure. Moreover, the extended use of calcineurin inhibitor immu...
Oral Quercetin Supplementation Lowers Plasma sICAM-1 Concentrations in Female db/db Mice
Quercetin Inflammation Insulin Resistance Obesity Adiponectin
2013/2/19
Background: Flavonoids are documented for their potential anti-adipogenic, anti-inflammatory and anti-diabetic effects. Quercetin, one of the most abundant flavonoids in edible plants, was investigate...
Ergogenic Capacity of a 7-Chinese Traditional Medicine Extract in Aged Mice
Antifatigue Antioxidant Chinese Traditional Medicine
2013/1/29
The ergogenic properties of a 7-Chinese traditional medicine water extract (Ligustrum lucidum ait, LLA), which is composed of the essences of Lycii fructus, Crataegi fructus, Phyllanthi fructus, Chrys...
Ultrastructural and morphometrical changes of mice ovaries following experimentally induced copper poisoning
Copper poisoning Electron microscopy Morphometry Ovary Mice
2015/9/28
Background: Copper (Cu) is an essential trace element involved in normal reproduction but its overexposure may produce some detrimental effects. The aim of this study was to investigate the effects of...
mGluR5 Knockout mice exhibit normal conditioned place-preference to cocaine
mGluR5 Knockout mice normal conditioned place-preference cocaine Neurons and Cognition
2012/4/28
Metabotropic glutamate receptor 5 (mGluR5) null mutant (-/-) mice have been reported to totally lack the rein- forcing or locomotor stimulating effects of cocaine. We tested mGluR5 -/- and +/+ mice fo...
中国医学科学院实验血液学国家重点实验室程韩忠朝课题组在Cell Transplant期刊上发表"Human umbilical cord mesenchymal stem cells ameliorate mice trinitrobenzene sulfonic acid (TNBS)-induced colitis"
韩忠朝 课题组 Cell Transplant期刊
2012/2/23
中国医学科学院实验血液学国家重点实验室韩忠朝课题组在Cell Transplant期刊上发表"Human umbilical cord mesenchymal stem cells ameliorate mice trinitrobenzene sulfonic acid (TNBS)-induced colitis."
Teratogenic and Embryotoxic Effects of Clomiphene Citrate in Developing Mice
Clomiphene Citrate Teratogenicity Embryotoxicity Mice Development
2016/5/6
The objective of this study was to assess the teratogenic and embryotoxic effects of clomiphene citrate in mice. The pregnant mice were administered a single dose of clomiphene citrate at different co...