搜索结果: 46-58 共查到“HDL”相关记录58条 . 查询时间(0.075 秒)
摘要 动脉平滑肌细胞（ＳＭＣ）是动脉粥样硬化（ＡＳ）斑块中的主要细胞，它的增殖在ＡＳ形成过程中极其重要。脂蛋白和氧化修饰型脂蛋白对ＳＭＣ增殖的影响以及ＳＭＣ增殖与原癌基因异常表达的关系是当前ＡＳ发病机制研究的热点之一。我们在建立人主动脉ＳＭＣ体外培养方法的基础上，观察了ＬＤＬ，ＶＬＤＬ及ＨＤＬ和相应的氧化修饰型脂蛋白对培养人ＳＭＣｆｏｓ，ｍｙｃ，ｅｒｂ－Ｂ原癌基因转录表达的影响。结果表明：①ＨＤＬ...
北京鸭血清HDL主要载脂蛋白的高效液相层析分离及其理化性质
北京鸭 脂蛋白 分离
2007/12/7
摘要 用高效液相层析(HPLC)对北京鸭血清高密度脂蛋白(HDL)的所有载脂蛋白(apo)分离纯化,得五个主要apo峰,经SDS-PAGE鉴定,均为单一带;并做了IEF、糖基含量分析;对其中含量高的四个apo峰样进行了氨基酸组成测定和N-端部分氨基酸序列分析;从所做理化性质的研究,发现北京鸭血清HDL中的主要apo为:A-Ⅰ、C-Ⅲ_o、apoC-Ⅲ_s(s=1,2)、apoC's及可能的A-Ⅲ,...
摘要 本文对北京鸭ａｐｏＡ－Ⅰ溴化氰裂解片段的理化性质、部分结构和抗原性以及其与鸭肝细胞膜ＨＤＬ受体的结合进行了研究。ａｐｏＡ－Ⅰ用溴化氰裂解后经ＨＰＬＣ分离得两个纯的肽段Ｐ５和Ｐ６，对二肽段作了氨基酸组成分析，并分别测定了Ｐ５，Ｐ６Ｎ端的１４和９个氨基酸残基序列。通过与鸡ａｐｏＡ－Ⅰ的比较，根据同源性及肽段大小，定出Ｐ５、Ｐ６分别位于鸭ａｐｏＡ－Ⅰ的第１３８－１７０ａａ和第７５－１３６ａａ的区域...
提出和实现了一种面向HDL描述基于路径覆盖的模拟矢量自动生成方法.该方法在约束生成时只考虑控制语句的条件表达式，可有效避免生成冗余约束；利用扩展的决策图模型解决了中间信号到初始输入的传播问题和信号依赖关系问题，以及处理各种HDL描述风格的问题；采用约束逻辑编程方法解决了由位、位向量和整型变量组成的约束系统的统一处理问题.实验结果表明该方法能加快模拟矢量生成速度，提高路径覆盖率.生成的模拟矢量也能用...
hs-CRP与TC/HDL-C联合检测在冠心病诊断中的应用
2007/7/25
近年来心血管疾病在我国已成为发病率及死亡率最高的疾病之一，其中冠状动脉粥样硬化性心脏病(CHD)作为主要的一种心脏病，越来越受到人们的关注[1][2][3][4][5]。慢性炎症是动脉粥样硬化发生和发展的一个重要组成部分。近年来不少新的炎症指标已不断应用于临床，但用来预测和诊断CHD都不能收到满意的效果。最近，超敏C-反应蛋白(high-sensitivity C-reactive protein...
VITAMIN E SUPPLEMENT BLOCKS THE RESPONSE OF HDL TO LOVASTATIN THERAPY IN HYPERCHOLESTROLEMIC PATIENTS
Vitamin E Lovastatin Hypercholesterolemia HDL-Cholesterol
2010/4/19
HDL can prevent LDL-c oxidation. The low HDL-c State also may benefit clinically from supplemented antioxidant. This study was designed to evaluate the combination therapy of statin and vitamin E in h...
Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipoproteins: a meta-analysis of 60 controlled trials
Diet fatty acids carbohydrates
2016/12/30
The effects of dietary fats on the risk of coronary artery disease (CAD) have traditionally been estimated from their effects on LDL cholesterol. Fats, however, also affect HDL cholesterol, and the ra...
Increase in Plasma HDL-Cholesterol Concentration in Goats Fed Sesame Meal Is Related to Ether Extract Fraction Included in the Meal
Sesame Meal Sesame Oil HDL-Cholesterol Goats
2016/4/13
Previously, we reported that a diet including sesame meal (SM) increased plasma total and high-density lipoprotein (HDL)-cholesterol concentrations in goats. In the present study, the components in th...
Alcohol-mediated enhancement of postprandial lipemia: a contributing factor to an increase in plasma HDL and a decrease in risk of cardiovascular disease
Alcohol postprandial lipemia reverse cholesterol transport
2017/1/4
We hypothesized that the alcohol-mediated increase in postprandial triacylglycerol-rich lipoproteins (TRLs) and their clearance elevate HDL cholesterol and reverse cholesterol transport.
Moderate intakes of intact soy protein rich in isoflavones compared with ethanol-extracted soy protein increase HDL but do not influence transforming growth factor β1 concentrations and hemostatic risk factors for coronary heart disease in healthy subjects
Isoflavones phytoestrogens genistein transforming growth factor β1 plasma lipids lipoproteins factor VII coagulant fibrinogen plasminogen activator inhibitor soy coronary heart disease coronary artery disease
2016/12/19
Background: Soybeans contain estrogenic isoflavones that may influence plasma concentrations of transforming growth factor β1 (TGF-β1) and plasma lipid and hemostatic risk factors for corona...
Dietary Sesame Meal Increases Plasma HDL-cholesterol Concentration in Goats
Sesame Meal Plasma HDL-cholesterol Goats
2016/4/12
Influence of dietary sesame meal on plasma glucose, non-esterified fatty acid (NEFA), triglyceride, total cholesterol, high-density lipoprotein (HDL)-cholesterol and urea concentrations in goats was e...
Polyunsaturated fatty acids modulate the effects of the APOA1 G-A polymorphism on HDL-cholesterol concentrations in a sex-specific manner:the Framingham Study
Polyunsaturated fatty acids modulate APOA1 G-A polymorphism HDL-cholesterol concentrations sex-specific manner Framingham Study
2016/12/17
Background: A common G-to-A substitution in the promoter area (−75 base pairs) of the apolipoprotein A-I gene (APOA1) has been described. The A allele was shown to be associated w...
HDL-cholesterol-raising effect of orange juice in subjects with hypercholesterolemia
Orange juice hypercholesterolemia lipoproteins, HDL cholesterol folate flavonoids vitamin C homocyst(e)ine
2016/6/8
Background: Orange juice—a rich source of vitamin C, folate,
and flavonoids such as hesperidin—induces hypocholesterolemic
responses in animals.
Objective: We determined whether orange juice benefi...