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Vitamin D insufficiency in children, adolescents, and young adults with cystic fibrosis despite routine oral supplementation1,2,3
Cystic fibrosis vitamin D fat-soluble vitamins children adolescents
2008/12/17
Background: Cystic fibrosis (CF) with pancreatic insufficiency is associated with poor absorption of fat and fat-soluble vitamins, including vitamin D. Pancreatic enzyme supplementation does not compl...
Efficacy of daily and monthly high-dose calciferol in vitamin D–deficient nulliparous and lactating women
Vitamin D deficiency 25-hydroxyvitamin D 25(OH)D lactating women nulliparous women
2008/12/12
Background: We previously found a high prevalence of vitamin D deficiency and low medication regimen compliance in Arab and East Indian women residing in the United Arab Emirates (UAE). The appropriat...
Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification
Aging anemia cognition disorders folate fortified food nutrition surveys vitamin B-12 deficiency
2008/12/12
Background:Historic reports on the treatment of pernicious anemia with folic acid suggest that high-level folic acid fortification delays the diagnosis of or exacerbates the effects of vitamin B-12 de...
Folic acid fortification: the good, the bad, and the puzzle of vitamin B-12
Folic acid fortification puzzle vitamin B-12
2008/12/12
We would not be allowed to conduct a clinical trial of a drug without proper monitoring procedures for both expected and unexpected outcomes; however, such a scenario occurred in 1998 when the Food an...
Carotene-rich plant foods ingested with minimal dietary fat enhance the total-body vitamin A pool size in Filipino schoolchildren as assessed by stable-isotope-dilution methodology
Vitamin A deuterated-retinol dilution stable-isotope dilution retinol plant carotenoids ß -carotene bioavailability
2008/12/12
Background:Strategies for improving the vitamin A status of vulnerable populations are needed.Objective:We studied the influence of the amounts of dietary fat on the effectiveness of carotene-rich pla...
Maternal vitamin D intake during pregnancy and early childhood wheezing1,2,3,4
Vitamin D intake pregnancy wheezing asthma
2008/12/12
Background: Maternal intake of vitamin D in pregnancy is a potentially modifiable but understudied risk factor for the development of asthma in children.Objective: We investigated whether maternal vit...
High prevalence of low dietary calcium, high phytate consumption, and vitamin D deficiency in healthy south Indians1,2
Dietary calcium phytate consumption vitamin D insufficiency bone mineral density Indians
2008/12/11
Background:Data on the vitamin D status of the population in a tropical country such as India have seldom been documented. Vitamin D deficiency is presumed to be rare.Objective:The objective was to do...
Holo-transcobalamin is an indicator of vitamin B-12 absorption in healthy adults with adequate vitamin B-12 status1,2,3
Transcobalamin holo-transcobalamin holo-TC vitamin B-12 vitamin B-12 absorption
2008/12/11
Background:It has been hypothesized that the response of holo-transcobalamin (holo-TC) to oral vitamin B-12 may be used to assess absorption. To develop a reliable clinical absorption test that uses h...
Potentially modifiable determinants of vitamin D status in an older population in the Netherlands: the Hoorn Study1,2,3
Vitamin D food fortification supplement use body fatness population-based study
2008/12/11
Background:Inadequate vitamin D status is common in many populations around the world. Objective:The aim was to evaluate potentially modifiable determinants of vitamin D status in an older population....
Randomized controlled safety and efficacy trial of 2 vitamin A supplementation schedules in Tanzanian infants1,2,3
Vitamin A supplementation safety efficacy Tanzania infants
2008/12/11
From the Ifakara Health Research and Development Centre, Ifakara, Tanzania (BI, HM, HU, EK, HM, and DMS); the St Francis Designated District Hospital, Ministry of Health, Ifakara, Tanzania (WB); the ...
Risk assessment for vitamin D1,2
Vitamin D risk assessment Tolerable Upper Intake Level UL
2008/12/10
The objective of this review was to apply the risk assessment methodology used by the Food and Nutrition Board (FNB) to derive a revised safe Tolerable Upper Intake Level (UL) for vitamin D. New data ...
Supplementation with calcium + vitamin D enhances the beneficial effect of weight loss on plasma lipid and lipoprotein concentrations1,2,3
Caltrate lipoproteins glucose insulin blood pressure
2008/12/10
Background: Adequate calcium intake can have a favorable effect on some metabolic variables.Objective: The objective of the study was to determine the effects of daily calcium intake and of supplement...
Supplementation with iron and riboflavin enhances dark adaptation response to vitamin A–fortified rice in iron-deficient, pregnant, nightblind Nepali women1,2,3
Pregnancy impaired pupillary threshold nightblindness iron deficiency riboflavin women Nepal
2008/12/10
Background:Nightblindness affects 16–52% of pregnant women in areas of Nepal and in some cases persists after vitamin A treatment. Iron and riboflavin affect vitamin A utilization and photoreceptor fu...
The contribution of plant foods to the vitamin A supply of lactating women in Vietnam: a randomized controlled trial1,2,3,4
Bioavailability vitamin A Vietnam breastfeeding women carotenoids food-based approaches
2008/12/10
Background: More information is needed on the efficacy of carotenoids from plant foods in improving vitamin A status.
Objective: We aimed to quantify the efficacy of provitamin A–rich vegetables and...
The urgent need to recommend an intake of vitamin D that is effective1,2
recommend an intake vitamin D effective
2008/12/9
The report by Hyppönen and Power in this issue of the Journal (1) highlights a frustrating and regrettable situation for nutrition researchers. In the early 1970s, the same serum 25-hydroxyvitami...