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In the male brown-Norway (BN) male rat, reproductive aging is associated with decreased LH-pulse amplitude and area
FSH testosterone pulsatile secretion
2009/2/17
The Brown-Norway (BN) rat has been proposed as a rodent model for the study of human male reproductive aging. As in man, reduction in serum or plasma testosterone (T) and both testicular (primary)...
Use of a rat cDNA probe specific for the Y chromosome to detect male-derived cells
Sty gene polymerase chain reaction
2009/2/17
A cDNA probe that exhibits specificity for the rat Y chromosome was generated by using a set of primers specific to the murine Sry gene, the sex-determining region of the Y chromosome. A 459-base pa...
Expression of clusterin/sulfated glycoprotein-2 under conditions of heat stress in rat Sertoli cells and a mouse Sertoli cell line
SGP-2 testis HSP7O
2009/2/17
Clusterin is the major protein produced by rat Sertoli cells and is deposited onto sperm membranes; however, its function is unknown. In order to gain insight into the regulation of clusterin in Serto...
The effects of spinal cord injury on the status of messenger ribonucleic acid for TRPM 2 and androgen receptor in the prostate of the rat
spinal cord messenger ribonucleic TRPM 2 rat
2009/2/17
The prostate is one of the male accessory sex glands that produce fluid components of the seminal plasma. In addition to androgen, a normal innervation of the prostate is believed to be important ...
Manidipine improves spermatogenesis in the stroke-prone spontaneously hypertensive rat
Testicular artery transferrin insulin-like growth
2009/2/17
We evaluated the protective effects of manidipine, which is a long-lasting calcium-channel blocker, against damage to spermatogenesis arising from hypertensive vascular changes in stroke-prone spo...
Partial sympathetic denervation of the rat epididymis permits fertilization but inhibits embryo development
Inferior mesenteric ganglion fertility spinal cord injury innervation spermatozoa intrauterine insemination
2009/2/17
The rat cauda epididymidis receives sympathetic innervation from the inferior mesenteric ganglion (IMG). We have previously demonstrated that surgical removal of the IMG and proximal hypogastric ner...
Androgenic regulation of NO availability in rat penile erection
Rats testosterone nitric oxide
2009/2/17
Prior studies from this laboratory, using untreated castrated (CASTRATE) rats and testosterone-treated castrated (TESTO) rats, have shown that the magnitude of the intracavernosal pressure increas...
Hormone treatment after irradiation stimulates recovery of rat spermatogenesis from surviving spermatogonia
Testis stem cells GnRH-agonist LHRH testosteron
2009/2/17
The possibility of stimulating the recovery of spermatogenesis after irradiation using hormone treatment was tested in LBNF, rats. At 10 weeks after irradiation with 3.5 Gy, the percentage of tubu...
Evaluation of the binding patterns of eleven FITC-conjugated lectins in Fischer 344 rat testes
eleven FITC-conjugated lectins Fischer 344 rat testes
2009/2/17
The binding patterns of 11 recently commercially available fluorescein isothiocyanate-conjugated lectins that have been uncharacterized or undercharacterized in rat testes and/or have an unknown or ...
Comparison of the response of rat testis and accessory sex organs to treatment with testosterone and the synthetic androgen methyltrienolone（R1881）
Androgens spermatogenesis testis prostate
2009/2/17
We have studied the ability of the synthetic androgen methyltrienolone (R1881) to maintain testis and accessory organ weights, as compared to the effect of testosterone propionate (TP). In contrast ...
Prevention of seminiferous tubular atrophy in a naturally cryptorchid rat model by early surgical intervention
Cryptorchidism orchiopexy testis descent
2009/2/17
In an attempt to determine whether the seminiferous tubular atrophy of the cryptorchid testis is preventable by early surgical correction of the cryptorchid state, aberrantly developed gubernacula d...
Isolation of highly purified type A spermatogonia from prepubertal rat testis
Type A spermatogonia cell separation c-kit cell culture
2009/2/17
We have developed a new method that allows isolation of highly purified type A spermatogonia from prepubertal rats. The procedure is based on the maximal release of spermatogonia from the seminifero...
P450 aromatase messenger ribonucleic acid expression in male rat germ cells: detection by reverse transcription-polymerase chain reaction amplification
Germ cells spermatids P450 aromatase estrogen
2009/2/17
We have previously demonstrated that cytochrome P450 aromatase (P450arom) protein, an estrogen-synthesizing enzyme, is present and active in germ cells of the adult mouse testis. To establish that P...
Pituitary control of proliferation and differentiation of Leydig cells and their putative precursors in immature hypophysectomized rat testis
Testis rat development Leydig cells steroidogenesis
2009/2/17
The objective of this study was to determine the effects of pituitary hormones (luteinizing hormone [LH], follicle-stimulating hormone [FSH], growth hormone [GH], and prolactin [PRL]) on interstit...
Ultrastructural observations of spermatogenesis following transplantation of rat testis cells into mouse seminiferous tubules
Testis spermatogenesis transplant rat mouse
2009/2/17
The testes of busulfan-treated immunodeficient mice receiving seminiferous tubule injections of testis cells from rats were examined by light and electron microscopy. The presence of active rat sper...