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Inflammatory mediators exert toxic effects of oxidative stress on human spermatozoa
Inflammatory factors reactive oxygen species peroxidative damage semen
2008/12/24
Epidemiological studies regarding male infertility have revealed that more and more infertile men suffer from acute or chronic inflammation of the genitourinary tract, which often occurs witho...
Sperm Characteristics and DNA Integrity of Iberian Red Deer（Cervus elaphus hispanicus）Epididymal Spermatozoa Frozen in the Presence of Enzymatic and Nonenzymatic Antioxidants
Cryopreservation fertilization gamete biology reproductive technology
2008/12/24
The main goal of this study was to investigate the potential protective effects of enzymatic and nonenzymatic antioxidants on cryopreservation injuries to red deer epididymal spermatozoa. In Expe...
The Analysis of Meiotic Segregation Patterns and Aneuploidy in the Spermatozoa of Father and Son With Translocation t（4;5）（p15.1;p12）and the Prediction of the Individual Probability Rate for Unbalanced Progeny at Birth
FISH risk assessment
2008/12/24
Reciprocal chromosomal translocations (RCT) have long been recognized as important etiological factors in reproductive failure. In the present study, the meiotic segregation patterns of the sperm...
Spermatozoa Have Decreased Antioxidant Enzymatic Capacity and Increased Reactive Oxygen Species Production During Aging in the Brown Norway Rat
Oxidative stress epididymis glutathione peroxidase superoxide dismutase reproduction sperm
2008/12/24
As the proportion of aged males attempting to reproduce continues to rise, so does the concern regarding the quality of spermatozoa from aged men. An imbalance between the generation of reacti...
Effect of Seminal Plasma Fractions From Entire and Vasectomized Rams on the Motility Characteristics, Membrane Status, and In Vitro Fertility of Ram Spermatozoa
Seminal Plasma Fractions Entire Vasectomized Rams Motility Characteristics Membrane Status
2008/12/24
Whole seminal plasma from ram semen collected before and after vasectomy was separated into 2 fractions, supernatant and pellet of vesicles, and their protein profiles characterized by one-dimens...
Sperm Sorting Procedure Induces a Redistribution of Hsp70 but Not Hsp60 and Hsp90 in Boar Spermatozoa
Flow cytometry heat shock protein 60 heat shock protein 70 heat shock protein 90 pig
2008/12/24
Heat shock proteins, besides their protective function against stresses, have been recently indicated as key factors for sperm fertilizing ability. Since sexing sperm by high-speed flow-cytometry su...
Immunolocalization and Possible Functional Role of PSP-I/PSP-II Heterodimer in Highly Extended Boar Spermatozoa
Reproductive tract semen sperm seminal plasma sperm capacitation
2008/12/24
PSP-I/PSP-II heterodimer is a major protein of boar seminal plasma which is able to preserve, in vitro, the viability, motility, and mitochondrial activity of highly extended boar spermatozoa for at...
Comparative Study of Four Different Sperm Washing Methods Using Apoptotic Markers in Ram Spermatozoa
Swim-up caspase activity annexin V
2008/12/24
The accurate measurement of semen fertilizing potential is of great importance in determining the acceptability of processed semen for breeding purposes. A good sperm preparation technique result...
Influence of Various Permeating Cryoprotectants on Freezability of Iberian Red Deer（Cervus elaphus hispanicus）Epididymal Spermatozoa: Effects of Concentration and Temperature of Addition
Ethylene glycol glycerol propylene glycol sperm cryopreservation
2008/12/24
With the aim of finding an ideal cryoprotectant (CPA) in a suitable concentration for red deer epididymal spermatozoa cryopreservation, we evaluated the effects of the 3 most commonly used CPAs, ...
Low Expression of Glycoprotein Subunit 130 in Ejaculated Spermatozoa from Asthenozoospermic Men
Interleukin-6 human spermatozoa motility
2008/12/24
Previous studies showed that interleukin-6 (IL-6) was expressed in human Leydig and Sertoli cells and that it inhibited sperm motility. The aim of this study was to compare the expression of I...
Sperm develop in the seminiferous tubules of testes following a complex developmental process called spermatogenesis. A series of morphologic remodeling occurs during spermiogenesis before the spe...
Changes in Membrane Lipid Order With Capacitation in Rhesus Macaque（Macaca mulatta）Spermatozoa
Primate sperm merocyanine 540 annexin-V tyrosine phosphorylation
2008/12/24
Lipophilic fluorescent dye merocyanine 540 is believed to stain cell membranes with increasing affinity as the lipid components become more disordered and has been associated with changes in m...
Hyperactivated Motility in Rhesus Macaque（Macaca mulatta）Spermatozoa
Primate sperm capacitation cyclic adenosine monophosphate caffeine
2008/12/24
Macaque spermatozoa can be capacitated according to a defined protocol and exhibit hyperactivated motility similar to that described in other species. The aim of this study was to create a method...
Sperm Nuclear Histone to Protamine Ratio in Fertile and Infertile Men：Evidence of Heterogeneous Subpopulations of Spermatozoa in the Ejaculate
Sperm DNA male infertility
2008/12/24
Sperm protamine deficiency is observed in a subset of infertile men, suggesting that the relative histone to protamine ratio may be altered in the spermatozoa of these men. We measured the ratio of ...
The Multi PDZ Domain Protein MUPP1 as a Putative Scaffolding Protein for Organizing Signaling Complexes in the Acrosome of Mammalian Spermatozoa
Signal transduction acrosome reaction MPDZ
2008/12/24
Spermatozoa undergo complex sequences of precisely timed events during the process of fertilization. These priming events, which comprise capacitation, egg recognition, acrosome reaction, and sperm-...