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The effects of the indazole carboxylic acid derivative, tolnidamine, on testicular function：I. Early changes in androgen binding protein secretion in the rat
tolnidamine rABP LH FSH testosterone
2009/2/20
The indazole carboxylic acid derivative, tolnidamine, has marked antispermatogenic activity in several animal species. In this study, we assessed the effect of tolnidamine on rat Sertoli cell functi...
Prostaglandin dehydrogenase activity of rat and rabbit testicular tissues and accessory glands before and after castration
Prostaglandin dehydrogenase activity rat rabbit testicular tissues
2009/2/20
Rat reproductive tissues contained both 15-hydroxy-prostaglandin dehydrogenase (PGDH) and delta 13-reductase activities, while rabbit tissues exhibited only PGDH activity. In the rat, delta 13-reduc...
Effects of induced hypoprolactinemia on testicular function during gonadal maturation in the rat
testes androgens bromocriptine prolactin
2009/2/20
We have evaluated the effects of hypoprolactinemia during gonadal maturation in the male rat. Intact 30-day-old rats were injected daily for 10 days with three different doses of bromocriptine (0.75...
Regional differences in luminal fluid polypeptides of the rat testis and epididymis revealed by two-dimensional gel electrophoresis
Regional differences luminal fluid polypeptides rat testis epididymis revealed two-dimensional gel electrophoresis
2009/2/20
Luminal fluid samples were collected by micropuncture of the seminiferous tubule, rete testis, and defined levels of the epididymal tubule. After removal of spermatozoa by centrifugation, the supernat...
Effects of long- and short-term vasectomy on structural and functional parameters of the rat
long- and short-term vasectomy structural and functional parameters rat
2009/2/20
The effects of vasectomy were examined by comparing various parameters from sham operated and vasectomized rats that had undergone surgery at 90 days of age and were killed at 190 or 390 days of age...
Protein secretion by the rat epididymis can be selectively modified in vitro by local anesthetics, glucose deprivation, dinitrophenol, ouabain, and ionophores
Protein secretion rat epididymis selectively modified local anesthetics
2009/2/20
Protein secretion by the caput epididymidis has been examined in vitro using radioactive methionine as a precursor for protein synthesis. Newly synthesized and secreted proteins were separated by gel ...
Fetal irradiation increases androgen production by dispersed leydig cells of the rat
seminiferous tubule damage fetal irradiation
2009/2/20
Damage to the seminiferous epithelium of the rat has been shown to decrease the concentration of serum testosterone. In these animals, compared to controls, the structure of the Leydig cells sugge...
Control of metastases in the Nb rat prostatic adenocarcinoma model
metastases Nb rat prostatic adenocarcinoma model
2009/2/20
Chemotherapeutic agents, as well as acetyl-salicylic acid, heparin, and indocin, were evaluated in regard to their effect on the rate of metastasis in the androgen-insensitive Noble rat prostate a...
Organ culture of rat caput epididymal tubules in a perifusion chamber
Organ culture rat caput epididymal tubules perifusion chamber
2009/2/20
We have been able to culture caput epididymal tubules from rats by modifying an organ culture system (Orgebin-Crist et al, 1980) which was used to culture rabbit corpus epididymal tubule segments. T...
The hormonal regulation of premeiotic steps of spermatogenesis in the newborn rat
mmature testis follicle stimulating hormone newborn rats testosterone propionate testicular
2009/2/20
the effect of high doses of testosterone propionate (TP) on the development of the first spermatogenic wave was systematically analyzed to determine the period of maximal susceptibility to testoster...
Regulation of rat caput epididymidis contractility by prostaglandins
epididymis sperm transport prostaglandins rat
2009/2/20
Mechanical activity of the rat caput epididymidis in vitro was recorded using a videomicrography system. The effects of prostaglandin (PG)F2 alpha, PGE2, and aspirin on caput epididymidis contractil...
Recovery of gonadal functions in the adult male rat following cessation of five-month daily treatment with an LHRH agonist
LHRH agonist testicular steroidogenesis ventral prostate seminal vesicles spermatogenesis
2009/2/20
This study describes the recovery of various parameters of the pituitary-gonadal axis following five months of daily treatment of adult male rats with a potent LHRH (luteinizing hormone-releasing ...
An experimental study of the effect of ischemia on testicular structure in the rat. Efficacy of intravenous inosine
ischemia inosine microsurgery testis autotranspiantation
2009/2/20
The damages caused by experimental testicular ischemia lasting 60 minutes have been examined in the rat. The histologic alterations of the germinal epithelium and of the tunica propria are studied...
Ultrastructure and intercellular vacuolization of isolated perfused and control rat testes
testis perfusion rat ultrastructure
2009/2/20
Isolated rat testes perfused in closed circuit with albuminated Krebs-Ringer bicarbonate buffer were examined by light and electron microscopic techniques in order to assess the structural integrity...
Structural features of cultured epithelial cells from the adult rat epididymis
epididymis epithelium primary culture
2009/2/20
Epithelial cells isolated from the caput epididymidis of adult rats were placed in primary culture and examined daily for ten days for changes in external anatomy, reorganization of cytoskeletal com...