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Relationship between sleep-related erections and testosterone levels in men
Testosterone range testosterone threshold hypogonadism night erections
2009/2/17
In order to identify a possible threshold for a serum testosterone level below which sleep-related erections are impaired and to compare this threshold with the normal laboratory range of testostero...
The number and magnitude of studies involving testosterone-supplementation therapy in older men are limited. In addition, many studies to date have not been blinded or controlled, were reported in...
Comparison of the response of rat testis and accessory sex organs to treatment with testosterone and the synthetic androgen methyltrienolone(R1881)
Androgens spermatogenesis testis prostate
2009/2/17
We have studied the ability of the synthetic androgen methyltrienolone (R1881) to maintain testis and accessory organ weights, as compared to the effect of testosterone propionate (TP). In contrast ...
Purification and characterization of a lipophilic factor from testicular macrophages that stimulates testosterone production by Leydig cells
Testis macrophage Leydig cell
2009/2/16
Testicular macrophages have been shown to secrete a factor that stimulates testosterone production by Leydig cells. The purpose of this investigation was to purify and characterize this factor. M...
The effects of recombinant FSH on testosterone-induced spermatogenesis in gonadotrophin-deficient(hpg)mice
Seminiferous tubule testis Sertoli cells FSH testosterone
2009/2/16
In order to clarify the mechanism of synergism between follicle-stimulatory hormone(FSH) and testosterone (T) in the hormonal regulation of spermatogenesis, we studied the effects of recombinant h...
Testosterone autoregulation of its biosynthesis in the rat testis:inhibition of 17 alpha-hydroxylase activity
1 7a-Hydroxylase testosterone autoregulation rat
2009/2/16
Using the in vitro perfused rat testis, the effects of testosterone (T) on its own biosynthesis, and in particular on the inhibition of specific steroidogenic step(s) in the biosynthetic pathway fro...
Hypoprolactinemia does not prevent restoration of normal spermatogenesis in gonadotropin-suppressed, testosterone-replaced rats
Spermatogenesis testosterone prolactin gonadotropin GnRH immunization
2009/2/16
We have previously shown that suppression of gonadotropins and spermatogenesis can be produced in rats by immunization against gonadotropin releasing hormone (GnRH). Administration of testosterone (...
Testosterone and spermatogenesis: evidence that androgens regulate cellular secretory mechanisms in stage VI-VIII seminiferous tubules from adult rats
Testosterone spermatogenesis androgens regulate cellular secretory mechanisms adult rats
2009/2/13
The aim of this study was to investigate the effect of testosterone manipulation on the quantitative synthesis and secretion of a number of specific proteins produced by seminiferous tubules (ST) ...
Intratesticular testosterone concentration following intratunical administration in the hypogonadal animal
Testosterone tunica vaginalis hypogonadism infertility
2009/2/13
The serum and intratesticular testosterone concentration (ITC) after testosterone administration in the tunica vaginalis (TV) sac compared to parenteral administration was studied in 20 dogs that were...
Age-related decreased Leydig cell testosterone production in the brown Norway rat
Aging Leydig cell testosterone LII Brown Norway
2009/2/13
Previous studies have demonstrated that Leydig cell testosterone production diminishes with age in Brown Norway rats. The objective of the studies presented herein was to test the following possible...
Testosterone regulation of proto-oncogene c-myc expression in primary Sertoli cell cultures from prepubertal rats
Cyclohexlmlde testis actinomycin-D
2009/2/13
The expression of c-myc has been associated with cell proliferation through changes of nuclear function. To evaluate the possibility that the proto-oncogene c-myc plays a role in testosterone-depend...
Changes in the endocrinological milieu after clomiphene citrate treatment for oligozoospermia:the clinical significance of the estradiol/testosterone ratio as a prognostic value
E5/T ratio clomiphene citrate male infertility
2009/2/12
We have already reported that the rate of increase in the estradiol/testosterone ratio (E2/T ratio) following human chorionic gonadotropin (hCG) injection has prognostic value in the treatment of olig...
Follicle-stimulating hormone(FSH)escape during chronic gonadotropin-releasing hormone(GnRH)agonist and testosterone treatment
GnRH agonist FSH male contraception spermatogenesis
2009/2/12
Observations that serum follicle-stimulating hormone (FSH) levels begin to rise after initial suppression during chronic gonadotropin-releasing hormone (GnRH) agonist treatment of men with prostat...
FSH is produced by GnRH-deficient men and is suppressed by testosterone
FSH GnRH-deficient men testosterone
2009/2/12
Because there is an unexpected action of testosterone (T) to increase follicle-stimulating hormone (FSH) production in the absence of gonadotropin-releasing hormone (GnRH) in the rat, the effects of T...
A ten-year safety study of the oral androgen testosterone undecanoate
safety study oral androgen testosterone undecanoate
2009/2/12
Testosterone undecanoate (Andriol) is an oral androgen that provides the hypogonadal patient with the unmodified testosterone molecule. It was introduced in the mid-1970s. This is a report on the safe...