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by Adult Rat Sertoli Cells：Effects of Testosterone Withdrawal and Replacement
Estradiol androgen testis protease inhibitor
2008/12/23
Protein C inhibitor (PCI), a member of the plasma serine protease inhibitor family, has been reported to be abundantly expressed in the seminal vesicles and testes. In this study, we examine the l...
Response: Responsiveness to Tamoxifen Citrate and Testosterone Undecanoate Is Independent of the Severity of Idiopathic Oligozoospermia
Tamoxifen Citrate Testosterone Undecanoate Idiopathic Oligozoospermia
2008/12/23
My confusion originates from the following wording: "total sperm count x 106/mL" present in the abstract and in table 1, page 916, of the Adamopoulos article (Adamopoulos et al, 2003). In this regar...
Responsiveness to Tamoxifen Citrate and Testosterone Undecanoate Is Independent of the Severity of Idiopathic Oligozoospermia
Tamoxifen Citrate Testosterone Undecanoate Severity Idiopathic Oligozoospermia
2008/12/23
In their recent article, "Cinnoxicam and L-Carnitine/Acetyl-L-Carnitine Treatment for Idiopathic and Varicocele-Associated Oligoasthenospermia," Cavallini et al (J Androl. 2004;761-770) made a refer...
Testosterone Administration Suppresses Adiponectin Levels in Men
Androgen hypogonadal leptin
2008/12/22
Testosterone (T) administration to men increases lean body mass and decreases fat mass. Adiponectin is produced by adipocytes and is thought to influence insulin sensitivity. In this study, we sou...
Temporal Relationships Among Testosterone Production, Steroidogenic Acute Regulatory Protein (StAR), and P450 Side-Chain Cleavage Enzyme（P450scc）During Leydig Cell Aging
Leydig cell cyclic AMP steroidogenesis Brown Norway rat
2008/12/22
Previous studies have shown that the capacity of Leydig cells from aged (21-24-month-old) Brown Norway rats to produce testosterone is reduced from young (4-month-old) levels, and that this is cor...
Rapid Glucocorticoid Mediation of Suppressed Testosterone Biosynthesis in Male Mice Subjected to Immobilization Stress
Leydig cell cyclic AMP glucocorticoid receptor
2008/12/22
Physical and psychosocial stress challenge homeostasis, increasing glucocorticoid secretion (in rodents, corticosterone [CORT]) while decreasing testosterone (T) levels. The dynamics of stress-induc...
Restorative Increases in Serum Testosterone Levels Are Significantly Correlated to Improvements in Sexual Functioning
Randomized controlled trial androgen gel hypogonadism sexual dysfunction
2008/12/22
It is recognized that testosterone (T) levels decrease in men with age, as does sexual function. We hypothesize that T supplementation in hypogonadal men with sexual dysfunction will restore certain...
Intratesticular Testosterone Concentrations Comparable With Serum Levels Are Not Sufficient to Maintain Normal Sperm Production in Men Receiving a Hormonal Contraceptive Regimen
Intratesticular androgens spermatogenesis gonadotropins progestogens
2008/12/22
Intratesticular testosterone (ITT) is thought to play a key role in the control of spermatogenesis in man but is rarely measured. The purposes of this study were 1) to examine the relationship betwe...
Male Hormonal Contraception: Suppression of Spermatogenesis by Injectable Testosterone Undecanoate Alone or With Levonorgestrel Implants in Chinese Men
Androgens contraceptive progestins family planning
2008/12/22
Monthly injections of testosterone undecanoate (TU) act as a male contraceptive by reversibly suppressing spermatogenesis to azoospermia or severe oligoazoospermia in 95% of Chinese men. In 5% of ...
Flutamide Administration at 500 mg Daily Has Similar Effects on Serum Testosterone to 750 mg Daily
Prostate neoplasm antiandrogen hormone PSA androgen deprivation
2008/12/22
A prior comparison of 750 mg flutamide daily to 500 mg daily with an LHRH analog or orchiectomy showed no difference in effect on prostate specific antigen (PSA). However, any difference was likely ...
Comparison of Tamoxifen and Testosterone Propionate in Male Rats：Differential Prevention of Orchidectomy Effects on Sex Organs, Bone Mass, Growth, and the Growth Hormone–IGF-I Axis
Testis androgens estrogens aromatase osteoporosis prostate seminal vesicle
2008/12/22
Testis dysfunction can weaken bone and reduce muscle mass as well as impair sexual function. Testosterone (T) therapy has useful effects on sex organs, bone, and muscle in T-deficient males, but pro...
Preservation of Spermatogenesis in Spinal Cord Injured Rats With Exogenous Testosterone. Relationship With Serum Testosterone Levels and Cellular Localization of cAMP Responsive Element Modulator
Sertoli cells CREM sperm
2008/12/22
The current experiment examined the effects of exogenous testosterone (T) on spermatogenesis in rats with spinal cord injury (SCI) and their relationship with the cellular distribution of a cyclic AMP...
Testosterone，Sexuality，and Erectile Function in Aging Men
Testosterone Sexuality Erectile Function Aging Men
2008/12/19
Human aging is associated with many changes, which resemble those seen with deficiencies of sex steroids or growth hormone and with cortisol excess. Among these are decreases in lean body mass (LBM) a...
Chronic Administration of Atrial Natriuretic Peptide Reduces Testosterone Production of Testes in Mice
ANP spermatogenesis testosterone
2008/12/19
The purpose of the present study was to examine the effect of the long-term administration of human atrial natriuretic peptide (ANP) on testosterone production in male mice. Twenty-five mice recei...
Effect of Simulated Microgravity on Testosterone and Sperm Motility in Mice
Tail suspension space simulated weightlessness testicular function spermatogenesis mouse
2008/12/19
We examined changes in the serum testosterone level and in sperm in the testis and epididymis by using tail-suspended mice, which are a simulation model of the body fluid shift in space, to evalua...