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Consumption of foods rich in saturated fatty acids and cholesterol has long been recognized as an important precursor for the development of coronary heart disease; saturated fatty acids and choles...
Phytosterol feeding in human clinical trials has had generally small and inconsistent effects on serum cholesterol concentrations, raising doubts about the importance of phytosterols in natural die...
Dietary plant sterols (phytosterols) have been shown to lower plasma lipid concentrations in animals and humans. However, the effect of phytosterol intake from tall oil on cholesterol and phytoster...
Background: Plasma lipid and lipoprotein responses have been variable in dietary intervention studies.Objective: The objective of this study was to evaluate the effects of the National Cholesterol E...
Increasing body mass index (BMI) is associated with progressively lower serum HDL-cholesterol concentrations, although the underlying body-composition compartment accounting for this unfavorable li...
Cholesterol-lowering diets are the mainstay of therapy for hypercholesterolemia. In this issue of the Journal, Kris-Etherton et al present an important meta-analysis summarizing the effectiveness o...
Full-fat sitostanol estercontaining margarine reduces serum total and LDL cholesterol, but the effect of plant stanol estercontaining margarine as part of a low-fat, low-cholesterol diet has not ...
We examined the cholesterol-lowering effects of a proprietary Chinese red-yeast-rice supplement in an American population consuming a diet similar to the American Heart Association Step I diet usin...
Least-squares regression analyses were used to test the effect on blood lipids of pectin, oat bran, guar gum, and psyllium. Independent variables were type and amount of soluble fiber, initial chol...
Background: In general populations, the effects of dietary cholesterol on blood cholesterol concentrations are modest. However, the relation is stronger in those with an ɛ4 allele in the apolipop...
Background: Atherosclerotic cardiovascular disease is currently a cause of mortality in some parts of the world. The ATP-Binding Cassette Transporter (ABCA1) gene prepares instructions to produce the ...
We investigated the degree of genetic association between insulin resistance (IR) with type 2 diabetes mellitus (DM) and abnormalities in lipid metabolism in 42 patients. IR was assessed by fasting in...
The present study was designed to investigate antioxidant activity of aqueous extract of Monascus fermented Indian variety of rice in high cholesterol diet fed- streptozotocin (STZ) induced diabetic r...
Excess caloric intake and/or obesity currently remain the largest predisposing risk factors for the development of type 2 diabetes. Discerning the cellular and molecular mechanisms responsible and ame...
In this issue of the Journal, Fuller et al. (1) showed in a large cohort of 140 people with prediabetes or well-controlled type 2 diabetes that 12 eggs/wk for 3 mo did not elevate LDL cholesterol comp...

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