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The Detrimental Effect of Adversity on HIV Outcomes in the Era of Combined Anti-Retroviral Therapy
HIV Outcomes Psychosocial Adversity Adherence
2013/2/19
Socially disadvantaged individuals with HIV experience unacceptably high rates of AIDS and death. The authors developed an adversity index to quantify the impact of demographic and psychosocial factor...
Retention in HIV Care among Patients Testing Positive for HIV and Ineligible to Start Antiretroviral Therapy
Retention Attrition HIV Care Patients Nigeria
2013/2/19
Background: The failure to monitor and link patients from HIV testing to HIV care and retain them in care until they are eligible for ART is a major barrier to early ART initiation. This study evaluat...
Disclosing HIV to Infected Children in South Africa in the Era of HAART: A Grounded Theory Study on the Process, Reasons and Outcomes of Disclosure
HIV Infected Children Revealing the Diagnosis
2013/2/19
South Africa has seen an increasing population of children and adolescents accessing antiretroviral treatment (ART) in the past seven years. Many of these children are at the age when they should know...
Determinants of HIV/AIDS Awareness among Garments Workers in Dhaka City, Bangladesh
HIV/AIDS STDs Garments Workers in Bangladesh Logistic Regression Model
2013/2/19
The main purpose of this study is to find the awareness level as well as the determinants of awareness on HIV/AIDS among the garments workers in Dhaka City, Bangladesh. To do so, 200 garments workers ...
HDV-RNA and HBsAg Evolution during peg-IFN Treatment in Three HBV-HDV-HCV-HIV Coinfected Patients
Delta Hepatitis HIV Infection Interferon Treatment HDV Viral Load Quantitative HBsAg
2013/2/19
Background: Patients coinfected with HBV, HDV, HCV and HIV are usually excluded from clinical trials. Data on pegylated interferon treatment in this setting are limited, with predictive factors for HD...
HIV-complicated meningovascular syphilis: Atypical symptoms with promising result using low molecular weight heparin
Meningovascular Syphilis HIV
2013/2/20
Both WHO and the CDC of Taiwan have reports indicating a dramatic increase in incidence of both syphilis and HIV. With their co-infection, neurosyphilis will become a major issue, and meningovascular ...
抗HIV治疗失败后HIV1耐药基因的变异
获得性免疫缺陷综合征 抗病毒治疗 抗药性 微生物 耐药基因
2014/7/1
研究抗人免疫缺陷病毒（HIV)治疗失败后，HIV1遗传基因变异情况，并分析其耐药性。方法选取抗HIV治疗失败的57例患者(其中采用D4T/3TC/NVP治疗方案者45例，3TC/AZT/NVP方案者7例，3TC/TDF/克立芝方案者5例），从其血浆中提取病毒RNA，运用逆转录-聚合酶链反应（RTPCR）和套式PCR扩增HIV1 pol区基因片段,并对扩增的目的片段进行测序,将测序结果提交We...
JCB：揭示驱动蛋白帮助HIV病毒逃避巨噬细胞的破坏
JCB 驱动蛋白 HIV病毒 巨噬细胞
2012/11/9
在一项发表在Journal of Cell Biology期刊上的研究中，研究人员鉴定出一种被称作驱动蛋白(kinesin)的马达蛋白(motor protein)运送病毒HIV到细胞质膜上，从而有助于这种病毒逃避巨噬细胞的破坏。
云南西部两地区HIV阳性者弓形虫感染血清学调查
HIV 弓形虫 IgG抗体 云南
2012/11/1
采集2010年6月～2011年8月云南西部两个地州（大理、德宏）的HIV阳性者（927份）血清和HIV阴性者（80份）血清，用ELISA法检测血清中弓形虫IgG抗体。结果显示，两地区HIV阳性者和HIV阴性者的弓形虫特异性抗体IgG阳性率分别为35.1％（325/927）和23.8％（19/80）。HIV阳性血清的检测结果显示，德宏州和大理州的阳性率分别为30.3％（178/588）和43.4％（...
Second Generation of HIV Surveillance System:A Pattern for Iran
HIV/AIDS Surveillance system Iran
2015/9/25
Background: For the purpose of minimizing the HIV/AIDS epidemic effects, one of the programs is the promotion of scientific methods and setting of the suitable surveillance systems. The present resear...
社区美沙酮维持治疗者HIV/AIDS高危行为及影响因素
美沙酮维持治疗 HIV/AIDS高危行为 影响因素
2014/5/30
了解广东省参与社区美沙酮维持治疗者人类免疫缺陷病毒（HIV）/获得性免疫缺陷综合征（AIDS）高危行为的影响因素。方法 抽取广东省14家社区美沙酮门诊的7 288 例受治者在治疗入组时的调查数据，采用logistic回归分析高危行为的影响因素。结果 过去1个月注射吸毒者占80.24%，最近1次性行为使用安全套者占42.53%，HIV感染率为7.46%，丙型肝炎病毒（HCV）感染率为78.96%；多...
研究高效抗反转录病毒治疗（HAART）1年，对HIV/AIDS患者免疫重建效果的影响。方法确认人免疫缺陷病毒(HIV)感染者35例，检测CD4+T淋巴细胞<350/μL，开始HAART治疗，并于治疗0、6、12个月时分别检测其病毒载量及CD4+T淋巴细胞、CD8+T淋巴细胞、CD4+童贞细胞、CD4+记忆细胞、CD8+激活细胞计数。结果治疗前,HIV RNA处于高复制水平,平均(4.62±1.09...
中国科学院上海巴斯德研究所揭示宿主细胞限制HIV-1复制的新机制（图）
宿主细胞 艾滋病毒 艾滋病疫苗
2012/8/1
目前，艾滋病疫苗尚未取得根本性突破，针对艾滋病毒I型（HIV-1）感染的临床治疗药物主要通过抑制病毒蛋白的功能来抑制病毒的复制，如HIV-1逆转录酶及蛋白水解酶的抑制剂等。但这些针对病毒蛋白的药物易产生耐药性，并且毒副作用大，病人依从性差，难以取得预期的理想治疗效果。
了解河南省艾滋病(AIDS)高发区艾滋病病毒(HIV)感染者/AIDS患者社会支持状况及其影响因素,为进一步制定政策提供依据。方法 采用一般调查问卷和社会支持量表(SSRS)对146例HIV感染者/AIDS患者进行调查。结果 HIV感染者/AIDS患者社会支持各领域评分及总评分均低于国内常模,差异有统计学意义(P<0.05),AIDS患者社会支持得分为(32.93±5.74)分,低于HIV感染者的...